{"id":"W2031786121","doi":"10.1016/j.dnarep.2014.11.005","title":"Enforced telomere elongation increases the sensitivity of human tumour cells to ionizing radiation","year":2014,"lang":"en","type":"article","venue":"DNA repair","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer","funders":"Wellcome Trust; Wellcome","keywords":"Telomere; Telomerase; Biology; Clonogenic assay; Chromosome; Ionizing radiation; Cancer cell; Cancer research; Cell; DNA damage; Genetics; Cancer; DNA; Cell biology; Molecular biology; Irradiation; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002613036,0.0002022484,0.0002368987,0.0002118559,0.00008436779,0.0002839413,0.0001033266,0.0001972837,0.001829804],"category_scores_gemma":[0.0003086131,0.0001061337,0.0001811163,0.0001792738,0.0001410027,0.0001259514,0.0002723005,0.0005576244,0.0003066425],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001132419,"about_ca_system_score_gemma":0.0001292922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002466041,"about_ca_topic_score_gemma":0.0002812278,"domain_scores_codex":[0.999845,0.00003307904,0.00002648224,0.00002981257,0.00003532007,0.00003033379],"domain_scores_gemma":[0.9997222,0.00009479233,0.00006776693,0.00004862258,0.00002443111,0.00004219957],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001327379,0.00004063738,0.0006021425,0.00003762603,0.00001058976,0.00003413392,0.00002600832,0.00008020329,0.9972766,0.00005789323,0.00003074341,0.001670697],"study_design_scores_gemma":[0.00001353861,0.001434924,0.01216464,0.00002048698,0.00002960807,0.0002904009,0.00003084383,0.0004618985,0.9820678,0.00006829977,0.003411064,0.000006432782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911534,0.004814429,0.001934918,0.0000979661,0.00003810036,0.00002257036,0.0002392844,0.0001006035,0.0015989],"genre_scores_gemma":[0.9953152,0.001565157,0.001085827,0.00006739611,0.0000125936,0.00001783828,0.0004358104,0.00001638279,0.001483803],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001829804,"threshold_uncertainty_score":0.006121278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01293944341048416,"score_gpt":0.2579171597935878,"score_spread":0.2449777163831036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}