{"id":"W2031827468","doi":"10.1016/j.freeradbiomed.2007.01.018","title":"High levels of p66shc and intracellular ROS in permanently arrested early embryos","year":2007,"lang":"en","type":"article","venue":"Free Radical Biology and Medicine","topic":"Birth, Development, and Health","field":"Medicine","cited_by":111,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Guelph","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Ontario Ministry of Food and Agriculture; University of Guelph","keywords":"Embryo; Oxidative stress; Intracellular; Biology; Reactive oxygen species; Cell biology; Senescence; Apoptosis; Embryogenesis; Andrology; Population; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001362647,0.0001873422,0.0002795503,0.000432681,0.0003299253,0.0003831,0.0002748595,0.0003773268,0.002333706],"category_scores_gemma":[0.0002637538,0.0002493297,0.0001945579,0.0002056793,0.0003564437,0.0003111787,0.0003117037,0.001060373,0.0002855868],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003238397,"about_ca_system_score_gemma":0.0002306536,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0014096,"about_ca_topic_score_gemma":0.001318345,"domain_scores_codex":[0.999895,0.00001281294,0.00001207744,0.00002146832,0.00002465974,0.00003397642],"domain_scores_gemma":[0.999747,0.00005730932,0.00005670315,0.00003465953,0.00003680073,0.00006751953],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004936282,0.00002002893,0.0007660468,0.00002381851,0.000006783855,0.0002245238,0.00007335967,0.00003418644,0.9968176,0.0003500845,0.00005684398,0.001133082],"study_design_scores_gemma":[0.00002991632,0.0003250406,0.02883628,0.00001158951,0.00003475651,0.0005822688,0.0002784967,0.0005311071,0.9668288,0.0003978081,0.0021292,0.00001457848],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9937072,0.001655399,0.00230197,0.0001316451,0.00006546184,0.00001283815,0.0004739174,0.0000409063,0.001610632],"genre_scores_gemma":[0.9947039,0.0004582004,0.0008009456,0.00003620647,0.00001590118,0.00001746131,0.0003659169,0.00001967588,0.003581765],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002333706,"threshold_uncertainty_score":0.007807016,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02360099514520055,"score_gpt":0.3047966391597722,"score_spread":0.2811956440145716,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}