{"id":"W2031850927","doi":"10.1194/jlr.m055269","title":"Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice","year":2015,"lang":"en","type":"article","venue":"Journal of Lipid Research","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":49,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Deutsche Forschungsgemeinschaft; Canadian Institutes of Health Research; European Commission","keywords":"Ceramide; Biosynthesis; Enzyme; ATP synthase; Biochemistry; Endoplasmic reticulum; Lipid signaling; Heterologous; Biology; Chemistry; Cell biology; Apoptosis; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004098317,0.000107718,0.0004191223,0.001268393,0.0000454143,0.0000282039,0.0002320825,0.0001225112,0.0002162718],"category_scores_gemma":[0.003407315,0.00008656434,0.0001107405,0.001241185,0.0001866656,0.0003004976,0.00010881,0.0008149132,0.0000329766],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004120409,"about_ca_system_score_gemma":0.001038623,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001534449,"about_ca_topic_score_gemma":0.00001740322,"domain_scores_codex":[0.9964259,0.0003255926,0.0006708571,0.0001660562,0.002015025,0.0003965684],"domain_scores_gemma":[0.9967512,0.0003449491,0.0002303576,0.0001823965,0.002194721,0.0002963998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002510285,0.0007033905,0.07322454,0.000191556,0.00009395531,0.0001669036,0.0008493188,0.00001411216,0.9125324,0.00006214994,0.001609213,0.008042143],"study_design_scores_gemma":[0.003576614,0.001154338,0.2519056,0.0005452503,0.0000217583,0.0003403075,0.001342366,0.0003058088,0.7356724,0.00007932624,0.004934805,0.0001213916],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943162,0.0008753894,0.0001051234,0.003268659,0.0002081354,0.0002328906,0.000006085978,0.000005471364,0.0009820504],"genre_scores_gemma":[0.9977223,0.0003337557,0.0002393989,0.00002857522,0.0005760778,0.000005580754,0.00001517565,0.00002463791,0.001054446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1786811,"threshold_uncertainty_score":0.407912,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1159231770040867,"score_gpt":0.3626370631512879,"score_spread":0.2467138861472012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}