{"id":"W2031857756","doi":"10.1074/jbc.m303977200","title":"Protein Profiling with Epstein-Barr Nuclear Antigen-1 Reveals an Interaction with the Herpesvirus-associated Ubiquitin-specific Protease HAUSP/USP7","year":2003,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Viral-associated cancers and disorders","field":"Medicine","cited_by":227,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Tandem affinity purification; Biology; Protein arginine methyltransferase 5; Virus; Viral replication; Epstein–Barr virus; Ubiquitin; Cell biology; Protease; Molecular biology; Virology; Affinity chromatography; Gene; Genetics; Methylation; Biochemistry; Methyltransferase; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009405203,0.0001427824,0.0001897415,0.0002389428,0.0001211859,0.000236501,0.0001214043,0.0002296429,0.0004733156],"category_scores_gemma":[0.0001289421,0.00007803978,0.0001546631,0.0002713442,0.0001070301,0.0001194383,0.0001361646,0.0002126062,0.0001892576],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002228732,"about_ca_system_score_gemma":0.00007818294,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006078659,"about_ca_topic_score_gemma":0.0007999124,"domain_scores_codex":[0.9998912,0.00001474464,0.000004758313,0.0000223337,0.00004222128,0.0000247736],"domain_scores_gemma":[0.9999465,0.00001383505,0.00001392038,0.000003792243,0.000009390244,0.00001249921],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007713486,0.000008825057,0.001136373,0.00001642089,0.000007727339,0.00004679006,0.00001163458,0.00006076533,0.9977379,0.00003905826,0.0000213573,0.0008359725],"study_design_scores_gemma":[0.000004486321,0.00008925081,0.03932904,0.000004029978,0.00003058669,0.0004465253,0.00005297521,0.003041793,0.9547924,0.00007834756,0.002125521,0.000004902095],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965388,0.001035717,0.001602781,0.00003272378,0.00000358609,0.00000616284,0.0001893346,0.00001462643,0.000576228],"genre_scores_gemma":[0.9948946,0.0005867849,0.002814578,0.00003217387,0.000003160046,0.000008564017,0.0005381863,0.00000731592,0.001114566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006078659,"threshold_uncertainty_score":0.001617074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02518983813158813,"score_gpt":0.2611039403348748,"score_spread":0.2359141022032867,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}