{"id":"W2031924013","doi":"10.2174/0929867043455954","title":"Paclitaxel Antibody Conjugates and Trehalose for Preserving the Immunulogical Activity After Freeze-Drying","year":2004,"lang":"en","type":"article","venue":"Current Medicinal Chemistry","topic":"Freezing and Crystallization Processes","field":"Engineering","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Trehalose; Paclitaxel; Immunoconjugate; Chemistry; Cytotoxicity; Freeze-drying; Conjugate; Monoclonal antibody; In vitro; Antibody; Pharmacology; Biochemistry; Chromatography; Cancer; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002051555,0.0003306145,0.0002468195,0.0001788425,0.0001345575,0.0002313308,0.0001983984,0.000199073,0.001116724],"category_scores_gemma":[0.0002046306,0.0001035228,0.0002314087,0.0001634887,0.0001572,0.0002551494,0.0001591814,0.0004684801,0.0002800699],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000146269,"about_ca_system_score_gemma":0.00012015,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002889732,"about_ca_topic_score_gemma":0.0005293483,"domain_scores_codex":[0.9998848,0.00002669579,0.00001284202,0.00002397989,0.00003237389,0.00001915424],"domain_scores_gemma":[0.9999111,0.00002352632,0.00002902534,0.00001671229,0.00001204821,0.000007612635],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003692241,0.000009442752,0.0000445966,0.00002372867,0.000002496451,0.00003209166,0.000008807659,0.00006427259,0.9983172,0.00005491144,0.00001237057,0.001393112],"study_design_scores_gemma":[0.000002117796,0.00007103104,0.0001991528,0.000002418804,0.000004743862,0.00009489425,0.000002823401,0.0001301423,0.9987766,0.00001322503,0.0007012745,0.000001597223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9701249,0.003268476,0.0236361,0.0001333345,0.00004056705,0.0001019146,0.0002174885,0.0001467406,0.002330487],"genre_scores_gemma":[0.9710806,0.002398744,0.02265024,0.00007549005,0.00001739514,0.00006428287,0.0003350462,0.0000654739,0.003312766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001116724,"threshold_uncertainty_score":0.003735781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01181669897553187,"score_gpt":0.2632234720815111,"score_spread":0.2514067731059792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}