{"id":"W2031924013","doi":"10.2174/0929867043455954","title":"Paclitaxel Antibody Conjugates and Trehalose for Preserving the Immunulogical Activity After Freeze-Drying","year":2004,"lang":"en","type":"article","venue":"Current Medicinal Chemistry","topic":"Freezing and Crystallization Processes","field":"Engineering","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"","keywords":"Trehalose; Paclitaxel; Immunoconjugate; Chemistry; Cytotoxicity; Freeze-drying; Conjugate; Monoclonal antibody; In vitro; Antibody; Pharmacology; Biochemistry; Chromatography; Cancer; Immunology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001209506,0.0001537021,0.000146659,0.00001200478,0.000101168,0.00004124916,0.0001396546,0.0000650181,0.00004083564],"category_scores_gemma":[0.0001575793,0.0001088099,0.00004107217,0.00007740043,0.0001145486,0.00009400184,0.00004153155,0.0002129682,0.000001097227],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003252019,"about_ca_system_score_gemma":0.00002314905,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000005115889,"about_ca_topic_score_gemma":0.000001240484,"domain_scores_codex":[0.9993211,0.000006268456,0.0001447952,0.0001700503,0.000143296,0.0002144613],"domain_scores_gemma":[0.9995757,0.0001064449,0.00003095462,0.0001625722,0.0000449883,0.00007928949],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001754411,0.0002315929,0.006189328,0.009054131,0.0001401206,0.00001658683,0.001813184,0.002474013,0.9575798,0.0002810473,0.0009362064,0.02110857],"study_design_scores_gemma":[0.006235597,0.0002136407,0.01683165,0.0039957,0.0003988724,0.0001281287,0.001753051,0.01519861,0.9102558,0.01202735,0.03136201,0.001599576],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.96964,0.01504435,0.01413081,0.0002513837,0.0001818274,0.0001377694,0.00002153712,0.000154428,0.0004378573],"genre_scores_gemma":[0.9990281,0.0004982941,0.00007305761,0.00001705218,0.0002428379,0.00007222166,0.00002403943,0.0000178462,0.00002653878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04732396,"threshold_uncertainty_score":0.443714,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01181669897553187,"score_gpt":0.2632234720815111,"score_spread":0.2514067731059792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}