{"id":"W2031979429","doi":"10.1080/17458080500411965","title":"Structural characterization of novel gemini non-viral DNA delivery systems for cutaneous gene therapy","year":2006,"lang":"en","type":"article","venue":"Journal of Experimental Nanoscience","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Brookhaven National Laboratory","keywords":"Transfection; Lamellar structure; Gene delivery; Materials science; DNA; Cationic polymerization; Small-angle X-ray scattering; Absorption (acoustics); Biophysics; Self-assembly; Pulmonary surfactant; Crystallography; Scattering; Nanotechnology; Gene; Polymer chemistry; Chemistry; Biochemistry; Biology; Optics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009241182,0.0001162004,0.0001706575,0.00005978487,0.00006416382,0.00003325864,0.0002699815,0.0000706774,0.000003690301],"category_scores_gemma":[0.000008563366,0.00009373353,0.0001213571,0.00005969648,0.00009489105,0.00002494352,0.00003574218,0.00003605992,3.556966e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002321987,"about_ca_system_score_gemma":0.00008306365,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002480027,"about_ca_topic_score_gemma":5.282336e-7,"domain_scores_codex":[0.9990838,0.00001267569,0.0003924242,0.0001605817,0.0001913202,0.0001592227],"domain_scores_gemma":[0.9992312,0.000006927803,0.0004070409,0.000118383,0.0001946437,0.00004179159],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002675464,0.0001005467,0.0003385594,0.000004701636,0.00001355898,0.000002981545,0.00005129544,0.0001353998,0.9988185,0.00001049821,0.0001008778,0.0001556027],"study_design_scores_gemma":[0.0007291854,0.001499833,0.001039635,0.00002345371,0.000004948092,0.0002396236,0.0001087265,0.0008999325,0.995025,0.000002406631,0.0003188348,0.0001083984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960805,0.001156196,0.001804174,0.000009482864,0.0007179064,0.0001569363,0.00003955166,0.00000157525,0.00003373387],"genre_scores_gemma":[0.9987405,0.0001782759,0.0004736899,0.00005707873,0.0003524749,0.000004804076,0.00002685797,0.000009248396,0.0001570616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003793409,"threshold_uncertainty_score":0.3822342,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01382061326229435,"score_gpt":0.2565726696726506,"score_spread":0.2427520564103562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}