{"id":"W2032007643","doi":"10.1089/cbr.2008.0582","title":"Adenovirus-Mediated ING4 Expression Suppresses Pancreatic Carcinoma Cell Growth via Induction of Cell-Cycle Alteration, Apoptosis, and Inhibition of Tumor Angiogenesis","year":2009,"lang":"en","type":"article","venue":"Cancer Biotherapy and Radiopharmaceuticals","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Cancer research; Transfection; Genetic enhancement; Biology; Cell cycle; Angiogenesis; Tumor suppressor gene; Cell growth; Apoptosis; Pancreatic tumor; Viral vector; Growth inhibition; Pancreatic cancer; Cell culture; Carcinogenesis; Cancer; Gene; Recombinant DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008495594,0.0001474261,0.0002040433,0.00007655792,0.00007280861,0.00001421241,0.00004881573,0.00008794616,0.0000359423],"category_scores_gemma":[0.000009565956,0.0001258995,0.00004924633,0.0001186465,0.0001334344,0.00001933153,0.00001840243,0.00005045658,2.674078e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001941342,"about_ca_system_score_gemma":0.00005475764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000101269,"about_ca_topic_score_gemma":0.00000248182,"domain_scores_codex":[0.9991211,0.00008259532,0.0002234936,0.0002709443,0.000125549,0.0001763551],"domain_scores_gemma":[0.9995384,0.00001949073,0.0001111225,0.00011783,0.00008966187,0.0001234725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005636011,0.000166897,0.007709553,0.0001415256,0.00003841043,0.00000139703,0.0001246004,0.000006381179,0.9892794,0.000002843557,0.0001520442,0.001813293],"study_design_scores_gemma":[0.002070426,0.0004881393,0.006207071,0.00004150729,0.00003851911,0.000004855473,0.00002739452,0.00007056001,0.990658,0.00003447524,0.0002369778,0.0001220209],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9752569,0.02391886,0.0002328363,0.0001383105,0.00004272427,0.000275749,0.00009830185,0.000006467534,0.00002984811],"genre_scores_gemma":[0.9749776,0.02441464,0.0001697125,0.0001930813,0.0001275767,0.00003231012,0.00006157098,0.00001334224,0.00001021348],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001691272,"threshold_uncertainty_score":0.5134033,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01248812939198791,"score_gpt":0.2945440583604199,"score_spread":0.282055928968432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}