{"id":"W2032062578","doi":"10.3899/jrheum.080782","title":"The Hypoxic Synovial Environment Regulates Expression of Vascular Endothelial Growth Factor and Osteopontin in Juvenile Idiopathic Arthritis","year":2009,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministero dell’Istruzione, dell’Università e della Ricerca; Fondazione Italiana per la Lotta al Neuroblastoma","keywords":"Vascular endothelial growth factor; Osteopontin; CD68; Angiogenesis; Medicine; Synovial fluid; Synovial membrane; Pathology; Hypoxia-inducible factors; Peripheral blood mononuclear cell; Arthritis; Immunohistochemistry; Immunology; Biology; Internal medicine; VEGF receptors; Osteoarthritis; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008663082,0.0001878372,0.0001697945,0.0002079049,0.0001905848,0.000196845,0.00005287422,0.0001248962,0.0006469462],"category_scores_gemma":[0.0001951895,0.0001000357,0.00009289171,0.0001137435,0.0002007027,0.00009979984,0.0001315749,0.0001325965,0.0001292595],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001875348,"about_ca_system_score_gemma":0.0001162308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000853455,"about_ca_topic_score_gemma":0.001048608,"domain_scores_codex":[0.9998866,0.00002295249,0.000008372944,0.00002118473,0.00003191833,0.00002895601],"domain_scores_gemma":[0.9998966,0.00001095503,0.00004816939,0.000003349653,0.00001325741,0.00002768817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005720606,0.00003146103,0.02027231,0.00009576719,0.00001088148,0.0007732971,0.0001370013,0.0000562851,0.9744989,0.00002483897,0.00006139788,0.003465927],"study_design_scores_gemma":[0.00008375271,0.001226182,0.8688697,0.00003796483,0.00007705043,0.004045529,0.0006735479,0.0008153137,0.121952,0.0001107298,0.002096934,0.00001123989],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976608,0.001880369,0.0001850819,0.00001598397,0.000004285165,0.000005147655,0.00003737141,0.000007649923,0.0002034034],"genre_scores_gemma":[0.9990091,0.0004916811,0.0001861172,0.0000130683,0.00001143678,0.000008156951,0.00004999689,0.000001348359,0.0002290141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000853455,"threshold_uncertainty_score":0.002164245,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00805480794081457,"score_gpt":0.2296279911159254,"score_spread":0.2215731831751109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}