{"id":"W2032062578","doi":"10.3899/jrheum.080782","title":"The Hypoxic Synovial Environment Regulates Expression of Vascular Endothelial Growth Factor and Osteopontin in Juvenile Idiopathic Arthritis","year":2009,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Ministero dell’Istruzione, dell’Università e della Ricerca; Fondazione Italiana per la Lotta al Neuroblastoma","keywords":"Vascular endothelial growth factor; Osteopontin; CD68; Angiogenesis; Medicine; Synovial fluid; Synovial membrane; Pathology; Hypoxia-inducible factors; Peripheral blood mononuclear cell; Arthritis; Immunohistochemistry; Immunology; Biology; Internal medicine; VEGF receptors; Osteoarthritis; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001260441,0.0001120766,0.0005857563,0.0001143477,0.0001089002,0.000008127076,0.0001928501,0.00009799949,0.00004239526],"category_scores_gemma":[0.0004103265,0.00005960339,0.0001003561,0.00006651436,0.0002529248,0.00007754531,0.00005313579,0.0003969236,0.000004193105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003047472,"about_ca_system_score_gemma":0.00011103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004341957,"about_ca_topic_score_gemma":0.00001023766,"domain_scores_codex":[0.9981636,0.0003758334,0.0008147992,0.00008327798,0.0003286444,0.0002337779],"domain_scores_gemma":[0.998969,0.0002779604,0.0004241005,0.0002183923,0.00005452244,0.00005598927],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.004627166,0.0005761623,0.1460419,0.0002313081,0.0001970128,0.0001457806,0.00726318,0.00004295613,0.7479704,0.000968686,0.0006826666,0.09125278],"study_design_scores_gemma":[0.02315955,0.007383394,0.6734987,0.00388545,0.000165582,0.01468503,0.005436772,0.0003175359,0.254606,0.01029617,0.006063222,0.0005025661],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.979354,0.01853004,0.00004694806,0.001780054,0.00006183699,0.0001772532,0.000001298218,0.000003538994,0.00004504841],"genre_scores_gemma":[0.9737724,0.02610829,0.00003768037,0.00002671904,0.000009863304,0.000001650063,3.755644e-7,0.000008678072,0.00003432408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5274568,"threshold_uncertainty_score":0.2430556,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00805480794081457,"score_gpt":0.2296279911159254,"score_spread":0.2215731831751109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}