{"id":"W2032095308","doi":"10.1016/j.virol.2013.09.022","title":"Pandemic H1N1 influenza A directly induces a robust and acute inflammatory gene signature in primary human bronchial epithelial cells downstream of membrane fusion","year":2013,"lang":"en","type":"article","venue":"Virology","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"Toronto General Hospital; Toronto Rehabilitation Institute; University of Toronto; University Health Network","funders":"","keywords":"Biology; Signature (topology); Cell biology; Pandemic; Gene; Influenza A virus; Downstream (manufacturing); Inflammation; Virology; Immunology; Coronavirus disease 2019 (COVID-19); Virus; Genetics; Infectious disease (medical specialty); Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002267758,0.0004070614,0.0002921149,0.0002739321,0.0003397219,0.0003620562,0.0001346987,0.0004301284,0.002318573],"category_scores_gemma":[0.0001425522,0.0001708247,0.0005282009,0.0001878732,0.0003021974,0.0002089698,0.0003116121,0.0006408227,0.0006999776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003268506,"about_ca_system_score_gemma":0.0001956861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006294319,"about_ca_topic_score_gemma":0.001018996,"domain_scores_codex":[0.9996744,0.00006633127,0.00002297951,0.00004967613,0.00005542692,0.0001311414],"domain_scores_gemma":[0.9998641,0.0000341748,0.00002205235,0.00002296669,0.00001893564,0.00003772218],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003023923,0.00003217867,0.0002853856,0.0000247313,0.000003974951,0.00008445785,0.00002106384,0.00001862252,0.9987679,0.00004073491,0.00005622341,0.0003623141],"study_design_scores_gemma":[0.00007039629,0.001533715,0.04775961,0.00001331729,0.00002676001,0.0005626434,0.0004316694,0.0006162761,0.9466337,0.0001328463,0.002209259,0.000009788204],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954901,0.001120123,0.0008802381,0.0001269624,0.00009245261,0.00005405896,0.0006193969,0.00002992334,0.001586732],"genre_scores_gemma":[0.9955949,0.0005219733,0.0007025218,0.0001200919,0.00004020587,0.00006081493,0.001056551,0.000008036,0.001894927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002318573,"threshold_uncertainty_score":0.007756352,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02807750169782176,"score_gpt":0.2963678467250728,"score_spread":0.268290345027251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}