{"id":"W2032122056","doi":"10.1038/ncprheum0861","title":"Is a step-down regimen more effective than a step-up regimen in the treatment of early rheumatoid arthritis?","year":2008,"lang":"en","type":"letter","venue":"Nature Clinical Practice Rheumatology","topic":"Rheumatoid Arthritis Research and Therapies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; University of Toronto","funders":"","keywords":"Regimen; Rheumatoid arthritis; Medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00226992,0.0003985777,0.002148224,0.0004503809,0.001227668,0.001357209,0.001200953,0.01901034,0.006980752],"category_scores_gemma":[0.01550859,0.0002530466,0.001174015,0.0006068049,0.001441696,0.002221923,0.0004240915,0.01239091,0.002917626],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001448588,"about_ca_system_score_gemma":0.001201358,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001600036,"about_ca_topic_score_gemma":0.00401205,"domain_scores_codex":[0.9981542,0.0007473452,0.0002697443,0.0001851339,0.0004475882,0.0001958832],"domain_scores_gemma":[0.9934233,0.004926544,0.0003156532,0.0001165693,0.0006460618,0.0005718604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.005167023,0.0009321469,0.008687625,0.00147505,0.0003647471,0.01131271,0.0002254578,0.0005699515,0.002224342,0.007285204,0.5569829,0.4047728],"study_design_scores_gemma":[0.007702581,0.006184722,0.03501722,0.003574312,0.0009294603,0.03891264,0.00142331,0.001790102,0.001724812,0.03039888,0.8720053,0.0003367538],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.007873688,0.03180321,0.0004092501,0.9372258,0.01345432,0.00002415311,0.00009321037,0.00004680552,0.009069653],"genre_scores_gemma":[0.06511588,0.02767241,0.001678762,0.8322022,0.06621518,0.00008685728,0.00009601671,0.00003062774,0.006902017],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.01901034,"threshold_uncertainty_score":0.02335292,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0267089416044494,"score_gpt":0.3784749984857452,"score_spread":0.3517660568812958,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}