{"id":"W2032188532","doi":"10.1016/j.ejcb.2010.11.015","title":"Cellular prion protein localizes to the nucleus of endocrine and neuronal cells and interacts with structural chromatin components","year":2011,"lang":"en","type":"article","venue":"European Journal of Cell Biology","topic":"Prion Diseases and Protein Misfolding","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa; Ottawa Hospital","funders":"Juvenile Diabetes Research Foundation United States of America; Canadian Institutes of Health Research; University of Ottawa; Canadian Diabetes Association","keywords":"Cell biology; Chromatin; Biology; Histone; Lamin; Nuclear lamina; Nucleus; Nuclear localization sequence; Nuclear protein; Transcription factor; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002034852,0.0001121599,0.0001416378,0.0000353459,0.00004232969,0.0000108666,0.0001841319,0.00001775131,0.00001990005],"category_scores_gemma":[0.00002133753,0.00006760817,0.00003657531,0.00002894991,0.0001142947,0.000004946135,0.0001598443,0.00009217971,0.000001422782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002440209,"about_ca_system_score_gemma":0.00001576489,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006283464,"about_ca_topic_score_gemma":0.000001247396,"domain_scores_codex":[0.9991174,0.0003022786,0.0002552847,0.0001383988,0.00005690507,0.0001296934],"domain_scores_gemma":[0.9994472,0.000009645606,0.0002512429,0.0001235295,0.00006392799,0.0001045024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004605796,0.00001943881,0.0004705829,0.00002308288,0.00002729038,0.00003001483,0.0001223275,0.000006647336,0.989301,0.00001392726,0.00002706863,0.009498036],"study_design_scores_gemma":[0.0007245766,0.002341975,0.008015634,0.00004684646,0.00002147641,0.00008997133,0.00004547714,0.0000203079,0.9746976,0.00001777234,0.01387974,0.00009864895],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973255,0.001564711,0.0006145702,0.00005520272,0.000060144,0.0001484819,0.00001297839,0.000001693816,0.0002166658],"genre_scores_gemma":[0.9971377,0.0002441028,0.002405523,0.00009229605,0.00008299696,6.471145e-7,0.000005810536,0.00001407541,0.00001685305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01460343,"threshold_uncertainty_score":0.2756981,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01126535197387371,"score_gpt":0.2040711730483458,"score_spread":0.1928058210744721,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}