{"id":"W2032262403","doi":"10.1158/1538-7445.am10-2591","title":"Abstract 2591: Differential oncolysis by vesicular stomatitis virus in prostate cancers arising in transgenic mice","year":2010,"lang":"en","type":"article","venue":"Cancer Research","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Oncolytic virus; Vesicular stomatitis virus; Prostate cancer; Cancer research; Terminal deoxynucleotidyl transferase; Genetically modified mouse; Tramp; Prostate; Cancer; Biology; Virus; PTEN; Cancer cell; TUNEL assay; Medicine; Pathology; Transgene; Apoptosis; Virology; Immunology; Internal medicine; PI3K/AKT/mTOR pathway; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002814697,0.0005919156,0.0003888488,0.0008936329,0.000300555,0.0005492542,0.0004426792,0.0008645185,0.002926241],"category_scores_gemma":[0.0001405543,0.0004309595,0.0006740929,0.0003086422,0.0005313921,0.0003833731,0.0003110233,0.002068717,0.0009582379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006564729,"about_ca_system_score_gemma":0.0003572704,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001161825,"about_ca_topic_score_gemma":0.001224041,"domain_scores_codex":[0.9995399,0.00005131639,0.00004617584,0.0001265603,0.0001229055,0.0001131621],"domain_scores_gemma":[0.9996468,0.0000417285,0.0001240965,0.00003359701,0.00002824423,0.0001256156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000170345,0.00007321891,0.0001013641,0.00002401274,0.000005015931,0.00005885695,0.00002121103,0.00005002214,0.9987961,0.0001814723,0.00006012046,0.0004583199],"study_design_scores_gemma":[0.0000562385,0.001253576,0.002632884,0.00001506409,0.00002426208,0.0004525323,0.00005923451,0.0009884962,0.9912048,0.0001006484,0.00319971,0.00001259404],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852004,0.00106651,0.006793274,0.0003593511,0.0001712324,0.0001508905,0.003212268,0.0003880426,0.002658075],"genre_scores_gemma":[0.9736192,0.001187361,0.005043762,0.0001711122,0.00003867411,0.0003065424,0.003416169,0.0002297274,0.01598739],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002926241,"threshold_uncertainty_score":0.009789228,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02371709510788639,"score_gpt":0.3710636073440041,"score_spread":0.3473465122361177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}