{"id":"W2032265388","doi":"10.1139/v07-048","title":"Iodine-promoted Prins-cyclization of ketones — A facile synthesis of spirocyclic-4-iodo-tetrahydropyrans and 5,6-dihydro-2<i>H</i>-pyrans","year":2007,"lang":"en","type":"article","venue":"Canadian Journal of Chemistry","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Prins reaction; Iodine; Alcohol; Selectivity; Organic chemistry; Combinatorial chemistry; Catalysis","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008700598,0.0003423262,0.0007693887,0.0001445128,0.00008121573,0.00002540292,0.0005460467,0.0004248287,0.002357384],"category_scores_gemma":[0.001660692,0.0003605829,0.0002490906,0.0003364493,0.0005113646,0.0001101106,0.00003067699,0.0004261284,0.000001502909],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002112983,"about_ca_system_score_gemma":0.0007024434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006614091,"about_ca_topic_score_gemma":0.0003901888,"domain_scores_codex":[0.9973767,0.00002618064,0.001343975,0.0003077188,0.0004352154,0.000510199],"domain_scores_gemma":[0.996833,0.0004524569,0.001007941,0.0005124064,0.0003392963,0.0008549018],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006457147,0.00005909812,0.007412747,0.001090014,0.0001503617,0.0001022213,0.0005733376,0.00001495294,0.9860633,0.000004126459,0.00006206375,0.004403186],"study_design_scores_gemma":[0.0007159453,0.00001772662,0.0006247785,0.0006009138,0.0001625188,0.0006788428,0.0006329931,0.00003953525,0.9945828,0.0001030041,0.001542248,0.000298647],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.988226,0.0007132304,0.0007063375,0.0001446697,0.0000819839,0.00005089711,0.0001522307,0.00001458062,0.009910088],"genre_scores_gemma":[0.9972112,0.00007016013,0.002050558,0.00001330487,0.0002009417,0.00000156797,0.000008903393,0.00005136351,0.0003919909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009518097,"threshold_uncertainty_score":0.9998846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01030677685141555,"score_gpt":0.2304667357607794,"score_spread":0.2201599589093638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}