{"id":"W2032278379","doi":"10.1021/bi801328u","title":"Regulation of Sterol Transport between Membranes and NPC2","year":2008,"lang":"en","type":"article","venue":"Biochemistry","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Research Council Canada","keywords":"Sterol; Membrane; Chemistry; Biochemistry; Biophysics; Cell biology; Cholesterol; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003409862,0.0005795753,0.0003656414,0.0002794464,0.0005315254,0.0009407875,0.0004860376,0.0004278137,0.001093552],"category_scores_gemma":[0.0003591111,0.0002693515,0.0003707013,0.00023464,0.0004804779,0.0007112103,0.0006596753,0.0006562328,0.0005837404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001072477,"about_ca_system_score_gemma":0.0003969269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001204006,"about_ca_topic_score_gemma":0.001005297,"domain_scores_codex":[0.9996264,0.00006498193,0.00003990834,0.00009925955,0.0001193068,0.00005018605],"domain_scores_gemma":[0.9997762,0.00004266878,0.00006175481,0.00002834649,0.00004988924,0.00004108476],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007661922,0.000009431847,0.0001153418,0.00004849506,0.000004652319,0.00003938667,0.00001549208,0.00007106768,0.9984393,0.0003201422,0.00004643306,0.0008137261],"study_design_scores_gemma":[0.000006978868,0.00001894332,0.0009786065,0.000004128947,0.000005692174,0.00009012591,0.00001816929,0.001382848,0.9949143,0.0000753745,0.002498682,0.000006175132],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9761153,0.005659189,0.0127179,0.0003819251,0.0001182395,0.00004931703,0.0005255599,0.0002743981,0.004158112],"genre_scores_gemma":[0.9866081,0.00208457,0.00679904,0.00009878441,0.00001958488,0.00007056566,0.0006358176,0.00006660575,0.003616792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001204006,"threshold_uncertainty_score":0.007781446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02785252706142756,"score_gpt":0.2762087141534896,"score_spread":0.248356187092062,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}