{"id":"W2032355912","doi":"10.1111/tra.12199","title":"<scp>PIKfyve</scp> Inhibition Interferes with Phagosome and Endosome Maturation in Macrophages","year":2014,"lang":"en","type":"article","venue":"Traffic","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"The Scarborough Hospital; University of Toronto; Toronto Metropolitan University","funders":"Natural Sciences and Engineering Research Council of Canada; Ryerson University","keywords":"Phagosome; Endosome; Cell biology; Phagocytosis; Phosphatidylinositol; Biology; Lysosome; Phagolysosome; Biochemistry; Signal transduction; Intracellular; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002291086,0.000428758,0.0005960458,0.0002410339,0.0002162983,0.0002715976,0.0003463121,0.0005249232,0.00102499],"category_scores_gemma":[0.0001574122,0.0001480729,0.0004949499,0.0002340187,0.0003132412,0.000228251,0.0002236843,0.0008178393,0.0004095364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003783985,"about_ca_system_score_gemma":0.0004463762,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001451193,"about_ca_topic_score_gemma":0.001610153,"domain_scores_codex":[0.9996119,0.0000581773,0.00006281402,0.00005217876,0.00009225925,0.0001227038],"domain_scores_gemma":[0.9998957,0.00002063342,0.00002109311,0.00001413816,0.00001354265,0.00003488087],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006282528,0.00009454412,0.0001205063,0.00006645599,0.00001727609,0.0001025399,0.00001384212,0.0001101172,0.9970474,0.0001571991,0.0001953705,0.001446588],"study_design_scores_gemma":[0.00005826997,0.0006421687,0.002386449,0.000005913791,0.00001999519,0.0002534685,0.00001934744,0.0008606362,0.9929448,0.00005038164,0.0027506,0.000008058048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923765,0.002212715,0.001468517,0.0002963909,0.0000979422,0.00005802961,0.0008384142,0.000174465,0.002476953],"genre_scores_gemma":[0.9934739,0.001068054,0.001375211,0.0001497722,0.00002447315,0.0001211317,0.0009307548,0.00003506684,0.002821528],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001451193,"threshold_uncertainty_score":0.003428936,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004304943088585822,"score_gpt":0.1900423876837242,"score_spread":0.1857374445951384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}