{"id":"W2032412801","doi":"10.1016/s0022-2836(03)00588-6","title":"Target DNA Bending is an Important Specificity Determinant in Target Site Selection in Tn10 Transposition","year":2003,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Bacteriophages and microbial interactions","field":"Environmental Science","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"","keywords":"Tn10; Transposase; DNA; Transposable element; Biology; Genetics; Transposition (logic); Mutant; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003356392,0.00009892213,0.0001790902,0.0001250439,0.00003615369,0.0000125675,0.00008205475,0.0001019998,0.001065487],"category_scores_gemma":[0.00001494881,0.00008932282,0.00007904694,0.0001832655,0.0000394004,0.0001951231,0.00001006783,0.0002480359,0.0000113389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001923598,"about_ca_system_score_gemma":0.00001404451,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002441772,"about_ca_topic_score_gemma":0.0005828786,"domain_scores_codex":[0.9989647,0.0001724235,0.0004385077,0.000160211,0.00005725169,0.000206902],"domain_scores_gemma":[0.999661,0.000007836054,0.0002027775,0.00005776977,0.0000101697,0.0000604424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003848022,0.0001256487,0.06059987,0.000001546981,0.000004760554,0.0001065424,0.000242459,0.0002458994,0.9382451,0.00002471899,0.00001501286,0.0003499862],"study_design_scores_gemma":[0.0004991962,0.0004965495,0.2383978,0.00002394484,0.00001062711,0.0006024372,0.00006985105,0.0003124003,0.7552451,0.000895491,0.003288898,0.0001577269],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946353,0.00005766249,0.00478462,0.0001125737,0.000160286,0.00007090955,0.000008880526,0.000002673769,0.0001670246],"genre_scores_gemma":[0.9941647,0.00004991179,0.005529011,0.0002070745,0.0000211133,0.000001318263,0.000005903482,0.000008039281,0.00001294692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.183,"threshold_uncertainty_score":0.9998477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007443000425004508,"score_gpt":0.2551043896642536,"score_spread":0.2476613892392491,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}