{"id":"W2032451420","doi":"10.1158/0008-5472.can-08-2513","title":"Pretargeted Radioimmunotherapy Using Anti-CD45 Monoclonal Antibodies to Deliver Radiation to Murine Hematolymphoid Tissues and Human Myeloid Leukemia","year":2008,"lang":"en","type":"article","venue":"Cancer Research","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"National Institutes of Health; Lymphoma Research Foundation; National Cancer Institute; Damon Runyon Cancer Research Foundation","keywords":"Radioimmunotherapy; DOTA; Medicine; Cancer research; Transplantation; Monoclonal antibody; In vivo; Antibody; Streptavidin; Pretargeting; Chemistry; Immunology; Internal medicine; Biotin; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002279768,0.0001453797,0.0002766393,0.0001614067,0.0004826526,0.00003011268,0.0001229567,0.00007596093,0.000280605],"category_scores_gemma":[0.00004398176,0.0001386958,0.00004000654,0.0005054889,0.0002077099,0.00008134174,0.0000641974,0.0002597151,0.00002548864],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004794974,"about_ca_system_score_gemma":0.0002090235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004043181,"about_ca_topic_score_gemma":0.000002868232,"domain_scores_codex":[0.9984974,0.00004471823,0.000224644,0.0003876857,0.0004265455,0.0004189503],"domain_scores_gemma":[0.9990561,0.00005949982,0.00002600588,0.0002837222,0.0001981266,0.0003765296],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001743069,0.00005080137,0.01224354,0.0001023296,0.00005745859,0.00003822432,0.0005914597,0.0001508896,0.9818096,0.00006226195,0.001935244,0.002783873],"study_design_scores_gemma":[0.001282935,0.0001070373,0.03158782,0.0001332543,0.00002110016,0.0001859893,0.0000583897,0.0007007687,0.9401297,0.00002374737,0.0255824,0.0001868691],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9929507,0.004631488,0.0001278867,0.00119858,0.00002525395,0.0007010996,0.00002149934,0.00004897461,0.0002944655],"genre_scores_gemma":[0.9947956,0.00209548,0.001168714,0.0003140021,0.00032025,0.0001370533,0.00002252845,0.00003115402,0.001115193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04167992,"threshold_uncertainty_score":0.5655849,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1285516226418145,"score_gpt":0.4584482067561254,"score_spread":0.3298965841143109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}