{"id":"W2032456556","doi":"10.3390/ph4101381","title":"Lipothioureas as Lipids for Gene Transfection: A Review","year":2011,"lang":"en","type":"review","venue":"Pharmaceuticals","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Transfection; Thiourea; In vivo; In vitro; Linker; Chemistry; Biochemistry; Cell; DNA; Gene; Cell biology; Computational biology; Pharmacology; Biology; Biotechnology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003431255,0.001175509,0.001042996,0.001918299,0.0002426825,0.0007439357,0.0006806108,0.0008979796,0.002583166],"category_scores_gemma":[0.0002800627,0.0003423773,0.0003167913,0.002031505,0.0003433558,0.001217784,0.0004178868,0.001061218,0.002531707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005457165,"about_ca_system_score_gemma":0.0006053535,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007367729,"about_ca_topic_score_gemma":0.001184138,"domain_scores_codex":[0.9998767,0.00001656151,0.00001805989,0.00002623907,0.00004872842,0.00001355595],"domain_scores_gemma":[0.9998723,0.00005825504,0.00002215838,0.000004633253,0.00002926491,0.00001332644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008481267,0.0001738624,0.0001532808,0.01942296,0.00007381474,0.0003756997,0.00007384502,0.0009349455,0.01813682,0.004462491,0.01685191,0.9392556],"study_design_scores_gemma":[0.00002481802,0.0001987403,0.0005689096,0.001486984,0.00009117835,0.001580052,0.00005120211,0.0002539177,0.006023663,0.001369618,0.988318,0.00003287245],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00040078,0.9974216,0.0005701311,0.000107371,0.0001565336,0.00001114463,0.00002277372,0.00001614644,0.001293513],"genre_scores_gemma":[0.001372071,0.9968339,0.0006996642,0.00008318172,0.00007638143,0.00001930859,0.00004029331,0.000003102989,0.0008722256],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002583166,"threshold_uncertainty_score":0.008641601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1456258539701797,"score_gpt":0.444849601664675,"score_spread":0.2992237476944953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}