{"id":"W2032465323","doi":"10.1074/jbc.m808531200","title":"Intracellular Transport of Human Immunodeficiency Virus Type 1 Genomic RNA and Viral Production Are Dependent on Dynein Motor Function and Late Endosome Positioning","year":2009,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of British Columbia; McGill University","funders":"","keywords":"Dynein; Endosome; Dynactin; Cell biology; Biology; Virology; Microtubule; Intracellular","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001039604,0.0002278058,0.0001448105,0.0001341216,0.0001347417,0.0004452568,0.0001145682,0.0001990366,0.0004690963],"category_scores_gemma":[0.0001618228,0.0001372278,0.0001351862,0.00007524784,0.000191838,0.000241473,0.0002029417,0.000254822,0.0002957901],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004988344,"about_ca_system_score_gemma":0.0002097949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007160256,"about_ca_topic_score_gemma":0.0009103054,"domain_scores_codex":[0.9998702,0.00001516374,0.00001029619,0.00003387289,0.00004000657,0.00003048541],"domain_scores_gemma":[0.9999241,0.00001877384,0.00002100893,0.00001127786,0.00001111161,0.00001383139],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000314859,0.000005653773,0.0001300877,0.00001134246,0.000001416348,0.00003669203,0.000005103147,0.00002317649,0.9987894,0.0001249278,0.000008098301,0.000832782],"study_design_scores_gemma":[0.000006976434,0.00007072338,0.006909089,0.000003764272,0.000006998438,0.0003428757,0.00001655429,0.001054604,0.9901156,0.0001262282,0.001342337,0.000004338915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921257,0.002251514,0.003721468,0.00005723427,0.00001274191,0.00001486816,0.0001290405,0.00006140913,0.001626031],"genre_scores_gemma":[0.9953972,0.0006719054,0.001993435,0.00001466889,0.000003958417,0.00001355593,0.0002658176,0.00001497009,0.001624549],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007160256,"threshold_uncertainty_score":0.003619313,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01021847152520372,"score_gpt":0.2122130278580034,"score_spread":0.2019945563327997,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}