{"id":"W2032481539","doi":"10.1007/s12031-010-9461-7","title":"Neuroprotection Induced In Vitro by Ischemic Preconditioning and Postconditioning: Modulation of Apoptosis and PI3K–Akt Pathways","year":2010,"lang":"en","type":"article","venue":"Journal of Molecular Neuroscience","topic":"Cardiac Ischemia and Reperfusion","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Canada","funders":"","keywords":"Neuroprotection; PI3K/AKT/mTOR pathway; Protein kinase B; Pharmacology; Apoptosis; Reperfusion injury; Ischemic preconditioning; Ischemia; Endogeny; Medicine; Anesthesia; Chemistry; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004188432,0.0009596504,0.000759304,0.000367236,0.0004304984,0.0004585093,0.000303501,0.0004592468,0.002185312],"category_scores_gemma":[0.0002466487,0.0002751909,0.0006601026,0.000411745,0.0004203081,0.0008240353,0.0002802767,0.001413053,0.000302037],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004311611,"about_ca_system_score_gemma":0.0008137244,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000746329,"about_ca_topic_score_gemma":0.001121879,"domain_scores_codex":[0.9997675,0.00003633917,0.00002593554,0.00003167003,0.00003533937,0.0001031912],"domain_scores_gemma":[0.9998802,0.00001903143,0.0000284916,0.00002064704,0.00001774598,0.00003384329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.005390292,0.0003699855,0.0004358226,0.0002971998,0.00008321471,0.000237695,0.00008235573,0.0001951087,0.9837235,0.000842385,0.0003015632,0.008040867],"study_design_scores_gemma":[0.0003609478,0.001690607,0.007900896,0.0000353376,0.000188378,0.0003908263,0.00005654035,0.0008755183,0.9865357,0.0005002359,0.001450891,0.00001408375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9769703,0.01478758,0.003514383,0.000599288,0.000362818,0.0000752335,0.0004148147,0.0001005195,0.003175102],"genre_scores_gemma":[0.9923552,0.004209602,0.001411409,0.0001369029,0.00008155738,0.0001012349,0.0004477833,0.00001233516,0.001244055],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002185312,"threshold_uncertainty_score":0.007310629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00779773390091909,"score_gpt":0.2324958538596321,"score_spread":0.224698119958713,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}