{"id":"W2032497809","doi":"10.1016/j.neures.2010.12.011","title":"Cellular mechanisms by which lipoic acid confers protection during the early stages of cerebral ischemia: A possible role for calcium","year":2010,"lang":"en","type":"article","venue":"Neuroscience Research","topic":"Biochemical Acid Research Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Prince Edward Island","funders":"Atlantic Canada Opportunities Agency","keywords":"Depolarization; Excitatory postsynaptic potential; Glutamate receptor; Ischemia; Neuroprotection; NMDA receptor; Calcium; Anesthesia; Electrophysiology; Chemistry; Neurotransmission; Patch clamp; Membrane potential; Pharmacology; Internal medicine; Endocrinology; Neuroscience; Medicine; Biology; Biochemistry; Inhibitory postsynaptic potential","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00120343,0.0001439702,0.0001376279,0.00008205872,0.0005884701,0.0001022143,0.0007870343,0.0001958115,0.000008317033],"category_scores_gemma":[0.001648543,0.0001022304,0.00007755684,0.0005341186,0.0008574067,0.00001541769,0.0005880935,0.0007461652,0.000002876942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001692125,"about_ca_system_score_gemma":0.0001904559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009973181,"about_ca_topic_score_gemma":0.00002805118,"domain_scores_codex":[0.9975422,0.0001304131,0.0001870909,0.0006010443,0.0007763769,0.0007628556],"domain_scores_gemma":[0.9986414,0.00004249915,0.00005975784,0.0004979259,0.0006068795,0.0001515938],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001208715,0.00006819626,0.0004701011,0.00006420338,0.000006102307,5.11717e-7,0.00003743467,0.000001227753,0.998638,0.00008823245,0.000328329,0.0001767615],"study_design_scores_gemma":[0.000328345,0.0007066164,0.0008410739,0.000006858001,0.000002650554,0.000004040227,0.000101013,0.0001897726,0.9960464,0.0001935587,0.001472614,0.0001070091],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962791,0.0001353459,0.001311893,0.001013191,0.0001196839,0.0009182079,0.00006274166,0.00001284142,0.0001470009],"genre_scores_gemma":[0.9980884,0.00003899584,0.0001782644,0.00002520104,0.0001118325,0.0003269538,0.000007155479,0.00002101648,0.001202245],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00259158,"threshold_uncertainty_score":0.4526096,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03132100044513383,"score_gpt":0.3221239983871653,"score_spread":0.2908029979420315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}