{"id":"W2032503173","doi":"10.1016/j.jalz.2010.08.040","title":"S4‐03‐01: Genome Wide Association Study in Late‐onset Alzheimer'S Disease Among Caribbean Hispanics Supports Clu, Picalm, Bin1, And Cugbp2 And Identifies Novel Loci","year":2010,"lang":"en","type":"article","venue":"Alzheimer s & Dementia","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Genome-wide association study; Single-nucleotide polymorphism; Genotyping; Biology; Genetic association; Genetics; Candidate gene; Allele; Genotype; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005000462,0.0004156021,0.0004051441,0.0009830119,0.0008658734,0.000945761,0.0005205981,0.0004330914,0.007791709],"category_scores_gemma":[0.001865489,0.0001385601,0.0004532533,0.001859624,0.0002378422,0.0002220176,0.0008155692,0.0005148437,0.0005597008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004411215,"about_ca_system_score_gemma":0.0007337368,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.06404243,"about_ca_topic_score_gemma":0.07649322,"domain_scores_codex":[0.9997471,0.00005984131,0.00002071973,0.00008885779,0.00003723109,0.00004623213],"domain_scores_gemma":[0.9993722,0.0001201481,0.000184262,0.0000654109,0.0001160907,0.0001418874],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002143006,0.00008688423,0.9320182,0.000333398,0.00137234,0.001982363,0.0007390887,0.0002403714,0.01110882,0.0009805048,0.008541752,0.0404534],"study_design_scores_gemma":[0.0001330747,0.00004848671,0.9845025,0.000149036,0.0006409444,0.001022015,0.0006704554,0.0005444371,0.001381136,0.0005927999,0.01029576,0.00001937513],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9797513,0.002508307,0.001036905,0.00125874,0.00007153991,0.00003633708,0.009321501,0.00009879383,0.005916648],"genre_scores_gemma":[0.9906532,0.0009322615,0.000997865,0.0004956535,0.00006618722,0.00007321062,0.004534842,0.00005883463,0.00218808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06404243,"threshold_uncertainty_score":0.1273394,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01227947577158732,"score_gpt":0.2543508078396146,"score_spread":0.2420713320680273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}