{"id":"W2032545317","doi":"10.1155/2015/172302","title":"Development of a Model of Chronic Kidney Disease in the C57BL/6 Mouse with Properties of Progressive Human CKD","year":2015,"lang":"en","type":"article","venue":"BioMed Research International","topic":"Chronic Kidney Disease and Diabetes","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; St. Joseph’s Healthcare Hamilton","funders":"Canadian Institutes of Health Research; Canadian HIV Trials Network, Canadian Institutes of Health Research; Kidney Foundation of Canada; McMaster University","keywords":"Kidney disease; Medicine; Disease; Population; Fibrosis; Internal medicine; End stage renal disease; Genetically modified mouse; Bioinformatics; Transgene; Endocrinology; Pathology; Biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001225422,0.001335303,0.0009012715,0.002637356,0.001130643,0.000916501,0.001704852,0.002274927,0.006209753],"category_scores_gemma":[0.0004907316,0.00090924,0.0009902767,0.0008433122,0.0008957918,0.0009908094,0.0008474026,0.003244717,0.00214273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007168814,"about_ca_system_score_gemma":0.001032641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001351103,"about_ca_topic_score_gemma":0.002313993,"domain_scores_codex":[0.9989728,0.0001340365,0.0001527919,0.0002547326,0.0003114422,0.0001742297],"domain_scores_gemma":[0.9990232,0.0001201112,0.0002095575,0.0001343007,0.0001496793,0.000363072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001067125,0.002049753,0.0007026917,0.0002946694,0.00004278544,0.0006720752,0.000227383,0.0004498181,0.9827575,0.004484372,0.001043369,0.006208355],"study_design_scores_gemma":[0.00137152,0.007570125,0.01011141,0.0004993341,0.0003811948,0.005864989,0.0003608359,0.006858502,0.8741902,0.002784155,0.08983408,0.0001736114],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7747795,0.006902423,0.1685092,0.003695793,0.001861106,0.00391461,0.01207347,0.002825027,0.02543898],"genre_scores_gemma":[0.6536079,0.01098252,0.2414972,0.001973082,0.0003203952,0.008455551,0.01255313,0.0007608004,0.06984933],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006209753,"threshold_uncertainty_score":0.02077371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1732827026837693,"score_gpt":0.3954081983431434,"score_spread":0.2221254956593742,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}