{"id":"W2032586822","doi":"10.1359/jbmr.080228","title":"Prostaglandin D2 Receptors Control Osteoclastogenesis and the Activity of Human Osteoclasts","year":2008,"lang":"en","type":"article","venue":"Journal of Bone and Mineral Research","topic":"Bone Metabolism and Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Arthritis Network; Canadian Institutes of Health Research","keywords":"Receptor; Osteoclast; RANKL; Bone resorption; Prostaglandin E2 receptor; Chemistry; Endocrinology; Internal medicine; Cell biology; Osteoprotegerin; Resorption; Prostaglandin D2; Biology; Medicine; Activator (genetics)","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002890175,0.0002249331,0.0002504631,0.0003310706,0.0001413317,0.0004635354,0.000138237,0.0002115779,0.001548999],"category_scores_gemma":[0.000324815,0.00015482,0.0001998478,0.0002282177,0.000158995,0.0001443965,0.0002334261,0.0002239662,0.0004404967],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003206334,"about_ca_system_score_gemma":0.0003659902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001436667,"about_ca_topic_score_gemma":0.001947311,"domain_scores_codex":[0.9997571,0.00004759053,0.00002337902,0.00003318874,0.00007418814,0.00006458609],"domain_scores_gemma":[0.9999228,0.00001682331,0.00001614746,0.000007296661,0.00002035504,0.00001664558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004381688,0.00002830928,0.00217852,0.0002262747,0.00001155235,0.0003605519,0.00007120164,0.0001000933,0.9851783,0.0004090672,0.0004416378,0.01055636],"study_design_scores_gemma":[0.00043567,0.0008218447,0.1497073,0.00009752087,0.0001268537,0.003820592,0.0004267555,0.001461378,0.7653919,0.0008986075,0.0767611,0.00005036579],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8777453,0.1047425,0.006080271,0.0004395017,0.0001524711,0.0001475344,0.00181672,0.0001582203,0.008717442],"genre_scores_gemma":[0.9698533,0.01950982,0.002717919,0.0001388472,0.0000833685,0.00006632596,0.001061386,0.00001676753,0.006552112],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001548999,"threshold_uncertainty_score":0.005181968,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03095633157973933,"score_gpt":0.3153130361541291,"score_spread":0.2843567045743898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}