{"id":"W2032634575","doi":"10.1189/jlb.0213089","title":"Homologous recombination into the eosinophil peroxidase locus generates a strain of mice expressing <i>Cre</i> recombinase exclusively in eosinophils","year":2013,"lang":"en","type":"article","venue":"Journal of Leukocyte Biology","topic":"Asthma and respiratory diseases","field":"Medicine","cited_by":109,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Alberta","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; Center for Individualized Medicine, Mayo Clinic; National Institutes of Health; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Mayo Foundation for Medical Education and Research; Lung Association, Alberta and NWT; National Center for Research Resources; American Heart Association","keywords":"Cre recombinase; Biology; Eosinophil; Eosinophil peroxidase; Gene targeting; Transgene; Homologous recombination; Genetically modified mouse; Immunology; Locus (genetics); Molecular biology; Genetics; Gene; Cell biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005755748,0.0007482101,0.0004355286,0.0007549041,0.0002965828,0.0004692819,0.0008310826,0.0008174789,0.004759883],"category_scores_gemma":[0.0002455155,0.0005193872,0.0004597818,0.0002795972,0.0005478342,0.0004034123,0.0006280736,0.001461976,0.002121616],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001906471,"about_ca_system_score_gemma":0.000298264,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002480534,"about_ca_topic_score_gemma":0.0004445178,"domain_scores_codex":[0.999699,0.00005667631,0.00003838413,0.00008428542,0.00006025664,0.00006134421],"domain_scores_gemma":[0.9996814,0.00005316578,0.0001029192,0.00006724508,0.0000201356,0.00007511425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001316409,0.00009087428,0.0001652558,0.00004132578,0.000007016239,0.0001435213,0.00003611073,0.00006525789,0.9953983,0.0007515609,0.0001709937,0.002998121],"study_design_scores_gemma":[0.0002012193,0.0006502901,0.003201223,0.00003029809,0.0000408485,0.001554438,0.00004108733,0.001004857,0.9706956,0.0002568323,0.02230247,0.00002082502],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8271583,0.001223892,0.1538661,0.0006386536,0.0002204405,0.001557162,0.004744383,0.00188136,0.008709719],"genre_scores_gemma":[0.8362123,0.002744497,0.112178,0.0003611787,0.00008162712,0.001756625,0.008069627,0.0008409292,0.03775533],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004759883,"threshold_uncertainty_score":0.01592338,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01331048179340671,"score_gpt":0.2730880458790335,"score_spread":0.2597775640856267,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}