{"id":"W2032647092","doi":"10.1002/gcc.21981","title":"Shattered and stitched chromosomes—chromothripsis and chromoanasynthesis—manifestations of a new chromosome crisis?","year":2012,"lang":"en","type":"article","venue":"Genes Chromosomes and Cancer","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Chromothripsis; Chromosome; Biology; Chromosomal rearrangement; Genetics; Event (particle physics); Evolutionary biology; Karyotype; Gene; DNA; Genome instability","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001656368,0.000369515,0.0004311464,0.0001018576,0.0002177321,0.00006661149,0.0001493173,0.0001834178,0.0002532359],"category_scores_gemma":[0.00002272115,0.0003510703,0.00008844907,0.0001409134,0.0002281382,0.00005772346,0.0002457675,0.00009046143,0.000003611454],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000291923,"about_ca_system_score_gemma":0.0001602694,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004847984,"about_ca_topic_score_gemma":0.0001530328,"domain_scores_codex":[0.9983059,0.00006176126,0.000427859,0.0005053735,0.000184427,0.0005146716],"domain_scores_gemma":[0.998948,0.00003020119,0.0002110208,0.0003610068,0.00008477282,0.0003649916],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001288373,0.0002983207,0.1208583,0.0007918208,0.0008906594,0.00001276132,0.005185974,0.00003373116,0.8234327,0.001135202,0.005883104,0.04134858],"study_design_scores_gemma":[0.004754055,0.001077392,0.3089707,0.0003355772,0.0009450249,0.001300691,0.007101566,0.00008987102,0.5725335,0.0009304376,0.09961714,0.002344037],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9410795,0.05726906,0.00009383177,0.0006597867,0.0002045086,0.0002643864,0.0002197994,0.0000215375,0.0001876081],"genre_scores_gemma":[0.9762673,0.02068028,0.001135411,0.0003391609,0.0006829072,0.0000788777,0.00007053815,0.00005085178,0.0006947165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2508992,"threshold_uncertainty_score":0.9998941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01604822914686917,"score_gpt":0.2523530681288507,"score_spread":0.2363048389819816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}