{"id":"W2032647092","doi":"10.1002/gcc.21981","title":"Shattered and stitched chromosomes—chromothripsis and chromoanasynthesis—manifestations of a new chromosome crisis?","year":2012,"lang":"en","type":"article","venue":"Genes Chromosomes and Cancer","topic":"Genomic variations and chromosomal abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; CancerCare Manitoba","funders":"","keywords":"Chromothripsis; Chromosome; Biology; Chromosomal rearrangement; Genetics; Event (particle physics); Evolutionary biology; Karyotype; Gene; DNA; Genome instability","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002747461,0.0002712433,0.0003917356,0.000574987,0.00028801,0.0008682494,0.0003792607,0.001109005,0.001361619],"category_scores_gemma":[0.0006818355,0.0001376027,0.0002246414,0.0004452924,0.001759513,0.001528994,0.0006065866,0.0009325636,0.0002213149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000421871,"about_ca_system_score_gemma":0.0002314433,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005891709,"about_ca_topic_score_gemma":0.0006074865,"domain_scores_codex":[0.9998608,0.00002245929,0.00001498753,0.00003605225,0.00003677513,0.00002883976],"domain_scores_gemma":[0.9996815,0.00009423352,0.00009393985,0.00004111912,0.00002931888,0.00005999744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001600899,0.0001062076,0.08891719,0.001300014,0.0002654071,0.1073547,0.0026646,0.001182812,0.5297269,0.0528902,0.007470043,0.2065211],"study_design_scores_gemma":[0.0001134927,0.0009456887,0.2369296,0.0004095197,0.0002471806,0.4078534,0.005380354,0.001759955,0.1747416,0.05553392,0.1158074,0.0002779148],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8839463,0.08240569,0.01006826,0.01255724,0.0007552583,0.00004349713,0.0002020712,0.0002426765,0.009779029],"genre_scores_gemma":[0.9704031,0.02290038,0.002153537,0.001084916,0.0003953259,0.00001268058,0.00009642351,0.00002220706,0.002931451],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001361619,"threshold_uncertainty_score":0.004555047,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01604822914686917,"score_gpt":0.2523530681288507,"score_spread":0.2363048389819816,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}