{"id":"W2032717233","doi":"10.1016/j.intimp.2015.01.019","title":"Docosahexaenoic acid ester of phloridzin inhibit lipopolysaccharide-induced inflammation in THP-1 differentiated macrophages","year":2015,"lang":"en","type":"article","venue":"International Immunopharmacology","topic":"Phytochemicals and Antioxidant Activities","field":"Medicine","cited_by":32,"is_retracted":false,"has_abstract":false,"ca_institutions":"Dalhousie University","funders":"","keywords":"Docosahexaenoic acid; Chemistry; Pharmacology; Lipopolysaccharide; Phlorizin; Cyclooxygenase; Inflammation; Tumor necrosis factor alpha; Nimesulide; Biochemistry; Phorbol; Troglitazone; Arachidonic acid; Polyunsaturated fatty acid; Endocrinology; Fatty acid; Immunology; Biology; Peroxisome proliferator-activated receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002006195,0.0004981689,0.000538238,0.0003024378,0.0002195182,0.0002876211,0.0002404511,0.0004322705,0.00211556],"category_scores_gemma":[0.0001779839,0.0002879433,0.0004351836,0.0002181464,0.0003782723,0.0003488037,0.0002632049,0.001196124,0.0004676736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002129706,"about_ca_system_score_gemma":0.0005243421,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001078756,"about_ca_topic_score_gemma":0.001266419,"domain_scores_codex":[0.9998478,0.00002230034,0.00002020983,0.00001637667,0.00002402906,0.00006917556],"domain_scores_gemma":[0.9998703,0.00002241286,0.00001924091,0.00001770935,0.00001589662,0.00005456638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00360722,0.0003024527,0.0002324122,0.0001267949,0.00001732168,0.0001158455,0.00003877066,0.0000663104,0.992512,0.0001086244,0.00009150826,0.002780826],"study_design_scores_gemma":[0.000300936,0.002584832,0.004978035,0.0000141799,0.00005340769,0.0001458438,0.00009144262,0.0004235096,0.9899393,0.00006990331,0.001389401,0.000009122734],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934029,0.002782018,0.001149309,0.0002376499,0.0001892581,0.00004990723,0.0003109102,0.00005205949,0.001825928],"genre_scores_gemma":[0.9910473,0.00241363,0.001529192,0.0001517884,0.00006499942,0.00007705838,0.0005680168,0.00001067593,0.004137276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00211556,"threshold_uncertainty_score":0.007077217,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04200473714645619,"score_gpt":0.3329531983036346,"score_spread":0.2909484611571784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}