{"id":"W2032843039","doi":"10.1016/j.febslet.2006.03.031","title":"Reversible inhibition of caspase‐3 activity by iron(III)","year":2006,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Apoptosis; Caspase; In vivo; Caspase 3; Biochemistry; Poly ADP ribose polymerase; Chelation; Protein disulfide-isomerase; Caspase-9; Cell biology; Enzyme; Programmed cell death; Biology; Polymerase","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002271499,0.0003241625,0.0002646233,0.0001089632,0.0001166496,0.0002078663,0.0002339256,0.0003376974,0.001908168],"category_scores_gemma":[0.0001733351,0.000102786,0.000313513,0.0001072672,0.0002475223,0.0001820933,0.0001437944,0.000549825,0.0003257658],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003216965,"about_ca_system_score_gemma":0.0001821589,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004947543,"about_ca_topic_score_gemma":0.0007320337,"domain_scores_codex":[0.9998509,0.0000202435,0.00001680218,0.00002778588,0.00004308481,0.00004119942],"domain_scores_gemma":[0.999904,0.00002060315,0.00002728293,0.0000212487,0.00001445223,0.00001232638],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001807593,0.0000286525,0.00007246645,0.00005458882,0.000008636704,0.00006485445,0.000009992796,0.00003635539,0.9970566,0.0001331127,0.00006596064,0.002287903],"study_design_scores_gemma":[0.00001969037,0.0001543256,0.0003888374,0.000001732489,0.000004649925,0.0001338493,0.000002997643,0.0001287675,0.9982368,0.00003277679,0.0008940982,0.000001568994],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850884,0.004590009,0.00639419,0.0002092003,0.00008358031,0.00006898319,0.0003080182,0.0001523818,0.003105304],"genre_scores_gemma":[0.9933934,0.001115784,0.00269311,0.00004990257,0.00001230848,0.00002052764,0.0003646201,0.00001187154,0.002338432],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001908168,"threshold_uncertainty_score":0.006383419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003543822888920405,"score_gpt":0.2001466633855709,"score_spread":0.1966028404966505,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}