{"id":"W2032859358","doi":"10.1371/journal.pone.0032795","title":"Cell-Type Specific Roles for PTEN in Establishing a Functional Retinal Architecture","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Alberta; Université de Montréal; Montreal Clinical Research Institute; University of Calgary","funders":"National Eye Institute; March of Dimes Foundation; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Canadian Institutes of Health Research","keywords":"PTEN; Retina; Biology; Cell biology; Retinal; Tensin; Retinal ganglion cell; Inner plexiform layer; Axon guidance; Axon; Neuroscience; PI3K/AKT/mTOR pathway; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001766343,0.0004295707,0.0001526265,0.0003498661,0.000237611,0.0004580102,0.0002897404,0.000257347,0.001212832],"category_scores_gemma":[0.0001818627,0.0001335906,0.0002280326,0.0001372913,0.0004310069,0.0002917971,0.0003421312,0.0003986043,0.0004842551],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003000826,"about_ca_system_score_gemma":0.0003082572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004638057,"about_ca_topic_score_gemma":0.0006072454,"domain_scores_codex":[0.9998592,0.00001394487,0.00001558722,0.00003325162,0.00005301902,0.00002488041],"domain_scores_gemma":[0.9998136,0.00002552625,0.00005722663,0.00002543495,0.00002622506,0.00005202197],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004032656,0.000007638209,0.0005130767,0.00002577232,0.000002853107,0.0001213084,0.00001344445,0.00005656309,0.9978599,0.0005141271,0.00001728697,0.000827645],"study_design_scores_gemma":[0.00001242882,0.0001583556,0.01345565,0.000008739696,0.00003453177,0.00135462,0.00006069803,0.00157241,0.9802051,0.0002764003,0.002853141,0.00000789989],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862263,0.001445622,0.00895449,0.00008325458,0.00003221956,0.0000312527,0.0003150168,0.0001378175,0.002774093],"genre_scores_gemma":[0.9945693,0.000590177,0.002855127,0.00002530214,0.000008724561,0.00002088224,0.0002886201,0.00002237798,0.001619471],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001212832,"threshold_uncertainty_score":0.004057348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03062893642159013,"score_gpt":0.2110431786744108,"score_spread":0.1804142422528207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}