{"id":"W2032859358","doi":"10.1371/journal.pone.0032795","title":"Cell-Type Specific Roles for PTEN in Establishing a Functional Retinal Architecture","year":2012,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Children's Hospital; University of Alberta; Université de Montréal; Montreal Clinical Research Institute; University of Calgary","funders":"National Eye Institute; March of Dimes Foundation; National Institutes of Health; Natural Sciences and Engineering Research Council of Canada; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Canadian Institutes of Health Research","keywords":"PTEN; Retina; Biology; Cell biology; Retinal; Tensin; Retinal ganglion cell; Inner plexiform layer; Axon guidance; Axon; Neuroscience; PI3K/AKT/mTOR pathway; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001544652,0.00009465747,0.00009256267,0.00004545874,0.00004277681,0.00002068257,0.00008059127,0.00008337164,0.00005050595],"category_scores_gemma":[0.00006131936,0.00009136563,0.00003478735,0.00007388985,0.00002161393,0.000005902189,0.00003130679,0.00007868455,0.00001264072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009168484,"about_ca_system_score_gemma":0.00002979902,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002376953,"about_ca_topic_score_gemma":0.000008836765,"domain_scores_codex":[0.9993213,0.00001941831,0.0001150805,0.0001689311,0.0001252708,0.0002499672],"domain_scores_gemma":[0.9997383,0.00001712037,0.0000346405,0.0001063305,0.0000473051,0.00005634837],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006613715,0.0007208161,0.08624704,0.0000797947,0.00004603435,6.520217e-7,0.000193608,0.00002759265,0.9042755,0.0001034654,0.006572103,0.001071976],"study_design_scores_gemma":[0.002338694,0.0004630014,0.07897981,0.00013097,0.00006389609,0.000006743161,0.0004722532,0.00007903347,0.8400451,0.0006796613,0.0759905,0.0007503257],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921715,0.001954207,0.001404098,0.0001860045,0.00006914939,0.0001840438,0.00000517426,0.00000854932,0.004017336],"genre_scores_gemma":[0.9914494,0.00014792,0.006376788,0.0001252829,0.0003485161,0.00003003319,0.0002174847,0.00001677522,0.00128786],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06941839,"threshold_uncertainty_score":0.3725782,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03062893642159013,"score_gpt":0.2110431786744108,"score_spread":0.1804142422528207,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}