{"id":"W2032872213","doi":"10.1016/j.jim.2011.06.013","title":"Effective in vitro expansion of CD40-activated human B lymphocytes in a defined bovine protein-free medium","year":2011,"lang":"en","type":"article","venue":"Journal of Immunological Methods","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Héma-Québec","funders":"","keywords":"CD19; Bovine serum albumin; CD154; In vitro; CD40; Lymphocyte; Serum albumin; Albumin; Molecular biology; Chemistry; Chemically defined medium; Biology; Immunology; Biochemistry; Flow cytometry; Cytotoxic T cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004305368,0.0004654024,0.0003192937,0.0002319645,0.0001768856,0.0003950713,0.0003227016,0.000270581,0.001285363],"category_scores_gemma":[0.0002355314,0.0001325633,0.0002594505,0.0002234411,0.0001221709,0.0001651243,0.0003056425,0.0005828028,0.0005871424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001947684,"about_ca_system_score_gemma":0.0002103872,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006811504,"about_ca_topic_score_gemma":0.0009723855,"domain_scores_codex":[0.9997635,0.00007637277,0.0000218198,0.00002517995,0.00005833415,0.00005483337],"domain_scores_gemma":[0.9998603,0.00006805331,0.000008726387,0.00002382016,0.00001781127,0.00002137226],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002437817,0.00006772571,0.0000758113,0.00004132475,0.000003771529,0.00004814707,0.00004043828,0.0001332794,0.9980027,0.00007264189,0.00005297936,0.001217429],"study_design_scores_gemma":[0.00003345323,0.0003757102,0.0009602599,0.000008776715,0.00002206369,0.0001249424,0.00001693577,0.0005008833,0.9953489,0.00003053632,0.002574613,0.000002979249],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9765705,0.005167011,0.01240931,0.00008406721,0.0001106884,0.0002097798,0.0008950043,0.0001540704,0.004399586],"genre_scores_gemma":[0.9859363,0.00152453,0.006054227,0.00005255097,0.00003990173,0.0001290963,0.001985555,0.00004115398,0.004236663],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001285363,"threshold_uncertainty_score":0.004299998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0351770698516405,"score_gpt":0.3198589810803082,"score_spread":0.2846819112286677,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}