{"id":"W2033048991","doi":"10.1021/ja9044955","title":"Experimental Evidence for the All-Up Reactive Conformation of Chiral Rhodium(II) Carboxylate Catalysts: Enantioselective Synthesis of <i>cis</i>-Cyclopropane α-Amino Acids","year":2009,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":234,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Cyclopropane; Chemistry; Cyclopropanation; Enantioselective synthesis; Stereoselectivity; Reactivity (psychology); Catalysis; Carboxylate; Rhodium; Asymmetric induction; Stereochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004023208,0.0002476261,0.0006368452,0.00002517196,0.0001494278,0.00001425181,0.0007109526,0.0001030491,0.00001597531],"category_scores_gemma":[0.0005679909,0.0001502625,0.0009780306,0.0002923805,0.0004477361,0.0002851834,0.0001111209,0.0004771737,4.015195e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005383114,"about_ca_system_score_gemma":0.0001837432,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000774353,"about_ca_topic_score_gemma":3.203576e-7,"domain_scores_codex":[0.9979666,0.00004230684,0.0008342616,0.0001958972,0.0006676497,0.0002932935],"domain_scores_gemma":[0.9956486,0.0007480033,0.002677141,0.0003849828,0.0004560769,0.00008525984],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006741164,0.0001501284,0.00004952786,0.00005632135,0.0003366352,3.343199e-7,0.003971188,0.00001686482,0.9896562,0.00001740046,0.0003671793,0.004704176],"study_design_scores_gemma":[0.0005273786,0.0002518441,0.0002374342,0.0002175175,0.0003655046,0.0000884149,0.009466862,0.0001977906,0.9881155,0.00009445582,0.0002748795,0.0001623504],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978109,0.0004849748,0.0003736913,0.0006587519,0.0001165785,0.0002157573,0.00003003788,0.00001552025,0.0002937632],"genre_scores_gemma":[0.9978638,0.0002692981,0.001388086,0.0001794887,0.0002034562,0.00001831846,0.000002964167,0.00002063475,0.00005394754],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005495674,"threshold_uncertainty_score":0.6127526,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02165568771252843,"score_gpt":0.2931529650785479,"score_spread":0.2714972773660195,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}