{"id":"W2033051200","doi":"10.1016/j.biologicals.2012.09.010","title":"Health Canada/BIOTECanada Summit on regulatory and clinical topics related to subsequent entry biologics (biosimilars), Ottawa, Canada, 14 May 2012","year":2012,"lang":"en","type":"article","venue":"Biologicals","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Health Canada; University of Toronto; University Health Network; Health Sciences Centre; Mount Sinai Hospital; Western University","funders":"Health Canada","keywords":"Biosimilar; Summit; Medicine; Pharmacovigilance; Comparability; Product (mathematics); Interchangeability; Health care; Family medicine; Pharmacology; Political science; Drug","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01849561,0.001370448,0.0009123181,0.00231616,0.01403596,0.009073462,0.003398303,0.0151947,0.02585663],"category_scores_gemma":[0.01358455,0.0008599894,0.001471845,0.001674721,0.004370487,0.001469679,0.003386281,0.008298879,0.004818871],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.09342714,"about_ca_system_score_gemma":0.268571,"about_ca_topic_candidate":true,"about_ca_topic_consensus":true,"about_ca_topic_score_codex":0.9417433,"about_ca_topic_score_gemma":0.983914,"domain_scores_codex":[0.9809194,0.00105063,0.0004802898,0.0009759291,0.01119405,0.005379733],"domain_scores_gemma":[0.9793545,0.001933752,0.0006694932,0.000452286,0.0103259,0.007264002],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001048003,0.0000723078,0.0007840421,0.00009127488,0.000008505373,0.0001615491,0.0001529542,0.0001085588,0.0003989115,0.001894183,0.9885079,0.007714955],"study_design_scores_gemma":[0.00005122626,0.00004166719,0.005795603,0.0001506975,0.0000176081,0.0000468029,0.0005017561,0.0001119873,0.0006196094,0.0004327702,0.9921952,0.00003502809],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01329105,0.04735845,0.001918938,0.638262,0.03470901,0.002099971,0.01782925,0.0004933468,0.2440379],"genre_scores_gemma":[0.06781849,0.01720788,0.005396788,0.2136181,0.00448622,0.0005130394,0.01160055,0.0002457847,0.6791133],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.9065729,"threshold_uncertainty_score":0.6778645,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04073485605413039,"score_gpt":0.3199077062913483,"score_spread":0.2791728502372179,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}