{"id":"W2033085024","doi":"10.1016/j.ijpharm.2015.03.023","title":"Characterising the disintegration properties of tablets in opaque media using texture analysis","year":2015,"lang":"en","type":"article","venue":"International Journal of Pharmaceutics","topic":"Drug Solubulity and Delivery Systems","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Gates Cambridge Trust; Grand Challenges Canada; UNICEF; Department for International Development, UK Government; Bill and Melinda Gates Foundation; United States Agency for International Development","keywords":"Opacity; Analyser; Texture (cosmology); Dosage form; Materials science; Chromatography; Mathematics; Biomedical engineering; Chemistry; Computer science; Medicine; Physics; Artificial intelligence; Optics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002781946,0.0002764674,0.0002990322,0.0005920818,0.000207527,0.0004837195,0.0001959116,0.0002925684,0.001264512],"category_scores_gemma":[0.0007905271,0.0002111732,0.0004705411,0.0006884713,0.000273501,0.000321607,0.0001978046,0.0004330321,0.0002066588],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002187028,"about_ca_system_score_gemma":0.000196291,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002733395,"about_ca_topic_score_gemma":0.002512674,"domain_scores_codex":[0.9996883,0.00002390002,0.00002835438,0.00004754547,0.0001710543,0.00004089025],"domain_scores_gemma":[0.9996175,0.0001151696,0.0001358547,0.00001913054,0.00008692249,0.00002547878],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007963259,0.0000344757,0.002391279,0.0001034179,0.00001590298,0.00008437172,0.00009711347,0.0001922797,0.9874785,0.00004265641,0.0000453216,0.008718335],"study_design_scores_gemma":[0.00003980523,0.001435721,0.08688255,0.00001561819,0.0001208278,0.0003526902,0.0002659147,0.003680297,0.9052318,0.00004246784,0.00188845,0.00004377498],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950671,0.0007581225,0.002785306,0.00003102866,0.00001140323,0.00004340191,0.0003958256,0.0000264541,0.0008812933],"genre_scores_gemma":[0.9926521,0.0006419693,0.004630628,0.00002061096,0.000006358745,0.00003889202,0.0003518059,0.00002431761,0.001633408],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002733395,"threshold_uncertainty_score":0.00543499,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3195651961511576,"score_gpt":0.4734980580836027,"score_spread":0.1539328619324452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}