{"id":"W2033103016","doi":"10.1016/j.npep.2009.06.004","title":"The role of β-endorphin in the pathophysiology of major depression","year":2009,"lang":"en","type":"review","venue":"Neuropeptides","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":119,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University; University of Alberta","funders":"","keywords":"Psychology; Context (archaeology); Major depressive disorder; Neuroscience; Depression (economics); Anhedonia; Amygdala; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009627979,0.0002365996,0.0007148089,0.00009578108,0.00009227401,0.00002417429,0.001234392,0.00009258049,0.00001224427],"category_scores_gemma":[0.0009191757,0.0001066437,0.0003103243,0.0004128121,0.0002052095,0.00003695098,0.000159722,0.0003833705,0.00001693619],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006842436,"about_ca_system_score_gemma":0.00006851005,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002948368,"about_ca_topic_score_gemma":0.00001003076,"domain_scores_codex":[0.9968471,0.001633646,0.0006320353,0.00036249,0.0002788673,0.0002458729],"domain_scores_gemma":[0.996246,0.002416856,0.0005535707,0.0007397393,0.00002061405,0.00002315086],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004012129,0.00004944535,0.000006243236,0.0002814709,0.000001984452,0.00003208105,0.00003274362,0.000001545076,0.009909885,0.0003687815,0.00005635686,0.9892194],"study_design_scores_gemma":[0.0001107113,0.0002138463,0.000342591,0.001821416,0.00006114729,0.00005023557,0.00002705747,0.00000881896,0.003957904,0.0008562578,0.9924155,0.0001345449],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002353398,0.9953971,4.411331e-7,0.00001770063,0.00008789112,0.0005054288,0.00003464288,0.00001027187,0.001593129],"genre_scores_gemma":[0.00789081,0.9917607,0.00000549935,0.0001191974,0.00004753017,0.00005022215,0.000001683223,0.00002328243,0.0001010297],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9923591,"threshold_uncertainty_score":0.4348805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03576905138215518,"score_gpt":0.3102995168837342,"score_spread":0.274530465501579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}