{"id":"W2033149510","doi":"10.1074/jbc.c000146200","title":"The Caenorhabditis elegans Sex Determination Protein FEM-1 Is a CED-3 Substrate That Associates with CED-4 and Mediates Apoptosis in Mammalian Cells","year":2000,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Caenorhabditis elegans; Apoptosis; Cell biology; Substrate (aquarium); Biology; Chemistry; Genetics; Gene; Ecology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007860891,0.0003832733,0.0001990796,0.0003905398,0.0004132288,0.000237844,0.0001812153,0.0003058906,0.0007090809],"category_scores_gemma":[0.0001015173,0.0001337722,0.0002825648,0.0001506171,0.0001543501,0.000186202,0.0002084553,0.0003451624,0.0003589261],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004546974,"about_ca_system_score_gemma":0.0002551059,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009288954,"about_ca_topic_score_gemma":0.001286404,"domain_scores_codex":[0.9999247,0.00000442467,0.000005346554,0.00002106464,0.00002950153,0.00001500858],"domain_scores_gemma":[0.9999313,0.000005452219,0.00002620754,0.000004900705,0.00001505252,0.00001702575],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006430836,0.00001662432,0.001037217,0.00008935308,0.00001115814,0.0002900077,0.00002356214,0.0001325039,0.989044,0.0002727948,0.0002503869,0.008768089],"study_design_scores_gemma":[0.00002658367,0.000255545,0.04332493,0.00004023346,0.00003137886,0.003234987,0.00005179171,0.001911546,0.9215525,0.0003106836,0.02923418,0.00002551344],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9682844,0.01477729,0.01059573,0.000206834,0.00009448623,0.00005034385,0.001118768,0.0002995524,0.004572597],"genre_scores_gemma":[0.9791802,0.004353758,0.008094419,0.00007315823,0.000015532,0.00003108664,0.001963326,0.00001453665,0.006274086],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009288954,"threshold_uncertainty_score":0.003299057,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009518197662054492,"score_gpt":0.2097383693189525,"score_spread":0.200220171656898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}