{"id":"W2033150325","doi":"10.1387/ijdb.062153kb","title":"Genetic interaction between Lef1 and Alx4 is required for early embryonic development","year":2006,"lang":"en","type":"article","venue":"The International Journal of Developmental Biology","topic":"Wnt/β-catenin signaling in development and cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance","keywords":"Biology; Embryonic stem cell; Cell biology; Enhancer; Embryo; Homeobox; Vasculogenesis; Phenotype; Transcription factor; Yolk sac; Embryogenesis; Genetics; Gene; Stem cell; Progenitor cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001224164,0.0003815526,0.0002183974,0.0003640847,0.0002146551,0.0003364548,0.0003836784,0.0003557729,0.001764292],"category_scores_gemma":[0.0001617852,0.000267504,0.0001833776,0.0001146832,0.0003089931,0.0001705949,0.0005097589,0.0004779327,0.0005769936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005297225,"about_ca_system_score_gemma":0.0002924655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00102051,"about_ca_topic_score_gemma":0.001696436,"domain_scores_codex":[0.9997994,0.00002549154,0.0000193484,0.0000431576,0.00007202973,0.00004069156],"domain_scores_gemma":[0.999819,0.00003051794,0.00007034127,0.00001541382,0.00001101843,0.00005385666],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006243894,0.00000760477,0.0003352767,0.000009921206,0.000002721196,0.000103417,0.000006423792,0.00004734749,0.9985912,0.00006605082,0.00001449774,0.0007529426],"study_design_scores_gemma":[0.00002938088,0.0001050264,0.0191218,0.000007138913,0.00001908747,0.0007793804,0.00004310418,0.001491184,0.9741881,0.00009259278,0.004113355,0.000009952468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993881,0.001052051,0.003156806,0.00007006201,0.00001451952,0.00001410123,0.0003987433,0.0001055897,0.001307126],"genre_scores_gemma":[0.9875534,0.0004615735,0.002916069,0.00003661139,0.000008515737,0.00002795709,0.0008553471,0.00005396121,0.00808651],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001764292,"threshold_uncertainty_score":0.005902171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01790053425379822,"score_gpt":0.2768270094880387,"score_spread":0.2589264752342405,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}