{"id":"W2033238968","doi":"10.1371/journal.pgen.1002632","title":"Phosphorylation of the Drosophila melanogaster RNA–Binding Protein HOW by MAPK/ERK Enhances Its Dimerization and Activity","year":2012,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"RNA Research and Splicing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; National Institute of General Medical Sciences; McGill University","keywords":"Biology; Phosphorylation; Cell biology; Drosophila melanogaster; MAPK/ERK pathway; Protein kinase A; Regulation of gene expression; Tyrosine phosphorylation; Signal transduction; RNA splicing; Kinase; Genetics; Gene; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009085488,0.0002469141,0.00009137324,0.00009896569,0.0001142782,0.0001607319,0.0001239247,0.0001182126,0.001510531],"category_scores_gemma":[0.00006511728,0.0001280149,0.0002070365,0.00004887661,0.000126179,0.0001303382,0.0002011531,0.0003025035,0.0003266615],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002052467,"about_ca_system_score_gemma":0.0001038752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000344654,"about_ca_topic_score_gemma":0.0007906009,"domain_scores_codex":[0.9999238,0.00001307982,0.00000648143,0.00001740927,0.00001717772,0.00002202303],"domain_scores_gemma":[0.9999359,0.000006970374,0.00001889028,0.000007617588,0.000005088888,0.00002555633],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003914838,0.000006635992,0.00009286516,0.0000154781,0.000002207886,0.00001367558,0.000004318847,0.0000257923,0.999406,0.0000620467,0.00002029162,0.0003114977],"study_design_scores_gemma":[0.00001543929,0.0001065125,0.01138556,0.000005531942,0.00001024022,0.0002110238,0.00002090578,0.001698125,0.9841148,0.00006243707,0.00236476,0.000004654854],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964387,0.000457465,0.001062433,0.00006491374,0.00001334221,0.00000666161,0.0001287384,0.00003316215,0.001794601],"genre_scores_gemma":[0.9969145,0.0001974845,0.0008548861,0.00003864478,0.000004246061,0.000006810691,0.0002298068,0.00001229532,0.001741232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001510531,"threshold_uncertainty_score":0.005053222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01562995322218837,"score_gpt":0.2405259416663855,"score_spread":0.2248959884441971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}