{"id":"W2033256968","doi":"10.1016/j.lfs.2012.10.014","title":"Evaluation of a novel poly N-acetyl glucosamine (pGlcNAc) hydrogel for treatment of the degenerating intervertebral disc","year":2012,"lang":"en","type":"article","venue":"Life Sciences","topic":"Spine and Intervertebral Disc Pathology","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre; University of Toronto","funders":"","keywords":"Aggrecan; Intervertebral disc; Proteoglycan; Extracellular matrix; Glycosaminoglycan; Viability assay; Self-healing hydrogels; Chemistry; Hyaluronic acid; In vitro; Tissue engineering; Cell biology; Glucosamine; Versican; Matrix (chemical analysis); Decorin; Biochemistry; Biophysics; Biomedical engineering; Pathology; Anatomy; Biology; Medicine; Polymer chemistry; Osteoarthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009323524,0.0000924182,0.0002362229,0.0000595184,0.00007646969,0.000003837725,0.0001240042,0.00003680485,0.00007205374],"category_scores_gemma":[0.0005334448,0.00004862033,0.0001734205,0.0002110524,0.0002620807,0.0001379988,0.00003507007,0.00001855028,0.000001584445],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000432915,"about_ca_system_score_gemma":0.0001831899,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001061051,"about_ca_topic_score_gemma":0.00005725276,"domain_scores_codex":[0.998899,0.0000489393,0.0002962758,0.0001442583,0.0004089192,0.0002025894],"domain_scores_gemma":[0.9994439,0.00001731387,0.0001711823,0.000168083,0.0001360494,0.00006340682],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004426562,0.002400189,0.1015904,0.0001050699,0.0001841991,1.431759e-7,0.003648409,0.00009781073,0.8386583,0.005162004,0.00055642,0.04755278],"study_design_scores_gemma":[0.005756584,0.00621204,0.2561152,0.0002184375,0.0007603333,0.00003778645,0.00199682,0.1016247,0.6268178,0.0001623204,0.000123837,0.0001741888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942167,0.002299652,0.0007464272,0.0006958454,0.0003623436,0.0004464215,0.00001964074,0.000006712351,0.001206188],"genre_scores_gemma":[0.9961041,0.000007143242,0.003350817,0.0001856553,0.000168706,0.000053306,0.000005873668,0.000004980638,0.0001193768],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2118406,"threshold_uncertainty_score":0.1982679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1768688550941336,"score_gpt":0.39407167512247,"score_spread":0.2172028200283365,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}