{"id":"W2033276865","doi":"10.1073/pnas.0813386106","title":"Genome-wide association and meta-analysis of bipolar disorder in individuals of European ancestry","year":2009,"lang":"en","type":"review","venue":"Proceedings of the National Academy of Sciences","topic":"Genetics and Neurodevelopmental Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":320,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Centre for Addiction and Mental Health","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Human Genome Research Institute; University of Michigan; Wellcome Trust; GlaxoSmithKline","keywords":"Single-nucleotide polymorphism; SNP; Genome-wide association study; Genetics; Biology; Genetic association; Candidate gene; Population; Bipolar disorder; Genetic genealogy; Genotype; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007696438,0.001938392,0.005394094,0.002817197,0.000952709,0.002571835,0.00143062,0.002224706,0.001982134],"category_scores_gemma":[0.01107365,0.001111661,0.01828763,0.004773666,0.0005236199,0.0007321303,0.001178129,0.001784019,0.0002397783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009076452,"about_ca_system_score_gemma":0.0008074639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01133883,"about_ca_topic_score_gemma":0.01229785,"domain_scores_codex":[0.9936653,0.003143323,0.0007152176,0.001732478,0.0004248763,0.0003187169],"domain_scores_gemma":[0.9950766,0.002803202,0.0006901504,0.0007940567,0.0004428204,0.0001931806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.007916403,0.00005448312,0.2871496,0.003790317,0.6820518,0.0006796827,0.0001357996,0.00258443,0.001401396,0.0003242956,0.002334829,0.01157696],"study_design_scores_gemma":[0.001106514,0.0003791823,0.2225656,0.0008238717,0.7673671,0.0005615829,0.0001427947,0.003195197,0.0005051401,0.001037105,0.002265314,0.0000505388],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.5264329,0.4582952,0.005192067,0.001847627,0.0008861048,0.0001195295,0.004979755,0.0002784599,0.001968219],"genre_scores_gemma":[0.9524032,0.04066129,0.002338995,0.0008018049,0.0003059822,0.0001511014,0.00272901,0.00008023273,0.0005283582],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.01133883,"threshold_uncertainty_score":0.04070312,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07243781901392782,"score_gpt":0.3299863593096236,"score_spread":0.2575485402956957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}