{"id":"W2033336824","doi":"10.1242/jeb.052803","title":"<i>In vivo</i>and<i>in vitro</i>assessment of cardiac β-adrenergic receptors in larval zebrafish (<i>Danio rerio</i>)","year":2011,"lang":"en","type":"article","venue":"Journal of Experimental Biology","topic":"Physiological and biochemical adaptations","field":"Environmental Science","cited_by":79,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Zebrafish; Danio; Gene knockdown; Biology; Receptor; Agonist; Cell biology; HEK 293 cells; In vivo; Morpholino; Molecular biology; Gene; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002639446,0.0001339836,0.0004006274,0.0000786094,0.00001627065,0.000003045825,0.0001999542,0.0001122597,0.0007662061],"category_scores_gemma":[0.00001903974,0.00009926005,0.00009783635,0.000223998,0.0002704956,0.0001473838,0.0001593677,0.000211987,0.000004037602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001451702,"about_ca_system_score_gemma":0.00001560957,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003856339,"about_ca_topic_score_gemma":0.00003581599,"domain_scores_codex":[0.9987097,0.0001539327,0.0005771988,0.0002057196,0.0001144278,0.0002390538],"domain_scores_gemma":[0.9995516,0.00005472141,0.0002143855,0.00008579992,0.000007083428,0.00008641199],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001744942,0.0004779315,0.03497589,0.000001709611,0.000006630641,0.000009225349,0.0002997633,0.000008717103,0.9636963,0.00009112123,0.0001253142,0.0001329054],"study_design_scores_gemma":[0.000558505,0.0004465022,0.0401961,0.00001608629,0.000003514097,0.000009175076,0.0003523217,0.00002763619,0.9567338,0.0008893494,0.000645328,0.0001217457],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968245,0.0003531172,0.000001470069,0.00007810238,0.000214436,0.00008892972,0.000008759347,0.000002517601,0.002428141],"genre_scores_gemma":[0.9969009,0.0001468504,0.002667822,0.000214352,0.00003140346,0.000008578692,0.000002459052,0.000005268889,0.00002241971],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00696256,"threshold_uncertainty_score":0.8389419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01696176897322022,"score_gpt":0.2598549524079548,"score_spread":0.2428931834347346,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}