{"id":"W2033380259","doi":"10.1002/path.1777","title":"PU.1 protein expression has a positive linear association with protein expression of germinal centre B cell genes including <i>BCL‐6, CD10, CD20</i> and <i>CD22</i> : identification of PU.1 putative binding sites in the <i>BCL‐6</i> promotor","year":2005,"lang":"en","type":"article","venue":"The Journal of Pathology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"BCL6; Germinal center; B cell; CD22; Molecular biology; Biology; Population; Follicular lymphoma; PAX5; Transcription factor; Cell; Gene; Diffuse large B-cell lymphoma; B-cell lymphoma; Lymphoma; Antibody; Genetics; Immunology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004185653,0.0002188664,0.0005518596,0.0003257922,0.0001750095,0.00002710525,0.0002847943,0.0001876422,0.00003799267],"category_scores_gemma":[0.0003304688,0.0001232595,0.0001005694,0.0004079728,0.0002689488,0.0002903673,0.00011218,0.0007388971,0.000002342524],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002101766,"about_ca_system_score_gemma":0.0002045703,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001474459,"about_ca_topic_score_gemma":0.00001789213,"domain_scores_codex":[0.9960912,0.001510015,0.0009372249,0.0002293715,0.0008925733,0.0003396207],"domain_scores_gemma":[0.9967111,0.0004845619,0.001833516,0.0002716664,0.0006187396,0.00008038567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002430343,0.0004764903,0.005061543,0.0001629545,0.00003397619,0.00009788186,0.01682612,0.00004480633,0.9725125,0.000004906176,0.00004887347,0.00229958],"study_design_scores_gemma":[0.002561123,0.001287055,0.00237069,0.0008567098,0.0001151015,0.0004362064,0.003463113,0.0001525089,0.988411,0.00007964855,0.0001549399,0.0001119171],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940028,0.0008445861,0.0003794049,0.002785621,0.00002685118,0.001811114,0.00002749258,0.000007428473,0.0001147211],"genre_scores_gemma":[0.9963346,0.000159729,0.002454785,0.00006533928,0.0001975022,0.00003795049,0.00001133501,0.00003122624,0.0007076084],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01589845,"threshold_uncertainty_score":0.5026377,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02743003368574839,"score_gpt":0.3033733703464049,"score_spread":0.2759433366606565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}