{"id":"W2033380259","doi":"10.1002/path.1777","title":"PU.1 protein expression has a positive linear association with protein expression of germinal centre B cell genes including <i>BCL‐6, CD10, CD20</i> and <i>CD22</i> : identification of PU.1 putative binding sites in the <i>BCL‐6</i> promotor","year":2005,"lang":"en","type":"article","venue":"The Journal of Pathology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"BCL6; Germinal center; B cell; CD22; Molecular biology; Biology; Population; Follicular lymphoma; PAX5; Transcription factor; Cell; Gene; Diffuse large B-cell lymphoma; B-cell lymphoma; Lymphoma; Antibody; Genetics; Immunology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001029525,0.0001780712,0.0001603405,0.0004208395,0.0001290443,0.0003237971,0.0001224319,0.0002178379,0.003139012],"category_scores_gemma":[0.0002554137,0.0001656299,0.000137043,0.0003017983,0.0002463418,0.0001998354,0.0002071465,0.000442341,0.0005835276],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001514598,"about_ca_system_score_gemma":0.0001109032,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003321144,"about_ca_topic_score_gemma":0.0003196528,"domain_scores_codex":[0.9998599,0.00001319492,0.000005889945,0.00004938207,0.00003709519,0.00003454968],"domain_scores_gemma":[0.9996965,0.00008976163,0.00009340455,0.00001796183,0.00003552117,0.00006689801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001078147,0.00002428512,0.00590045,0.00003944922,0.000008653489,0.00003309514,0.00003100621,0.00002403192,0.9916967,0.00003539573,0.00003923319,0.002059921],"study_design_scores_gemma":[0.00001657934,0.0006018677,0.3335522,0.00001367564,0.00003143153,0.001713424,0.0001063662,0.0009849312,0.6592823,0.0001389477,0.003547318,0.00001095682],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949007,0.001776772,0.002053767,0.00005496039,0.00001222144,0.00000793102,0.0002668104,0.00008943049,0.0008373988],"genre_scores_gemma":[0.9944554,0.0006167248,0.001633683,0.00002770997,0.00001118722,0.00002808534,0.0008537351,0.00001184768,0.002361661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003139012,"threshold_uncertainty_score":0.01050109,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02743003368574839,"score_gpt":0.3033733703464049,"score_spread":0.2759433366606565,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}