{"id":"W2033406567","doi":"10.1021/bc900192b","title":"Comprehensive Radiolabeling, Stability, and Tissue Distribution Studies of Technetium-99m Single Amino Acid Chelates (SAAC)","year":2009,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"U.S. Public Health Service","keywords":"Chemistry; Chelation; Amino acid; Biomolecule; Combinatorial chemistry; Lysine; Technetium; Carboxylate; Cationic polymerization; DOTA; Stereochemistry; Organic chemistry; Biochemistry; Nuclear chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005776296,0.0003983299,0.0003921519,0.0003601661,0.0002128177,0.0002331785,0.0002535354,0.0003095176,0.0004119076],"category_scores_gemma":[0.0004465605,0.0001476435,0.0002172414,0.0002698188,0.0002737232,0.0002388895,0.0002092467,0.0003219997,0.000189471],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003668855,"about_ca_system_score_gemma":0.0003111861,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001207837,"about_ca_topic_score_gemma":0.00121013,"domain_scores_codex":[0.9998277,0.00003662255,0.00001285481,0.00004582733,0.00005307321,0.00002387602],"domain_scores_gemma":[0.9996347,0.00007874752,0.00009383357,0.00003598592,0.0001175389,0.00003925201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000901047,0.00001130258,0.0001817284,0.0000402919,0.000007527622,0.00002498352,0.00002631031,0.0001717147,0.996989,0.0000408319,0.00003021309,0.002386041],"study_design_scores_gemma":[0.000005081021,0.0005421934,0.001121053,0.000002647868,0.00002268903,0.0002772895,0.00001090736,0.0005563902,0.9959174,0.00001787595,0.001520524,0.000005941986],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9772718,0.006166182,0.01476913,0.0000510062,0.00001710519,0.00007637466,0.0002425451,0.0001345773,0.00127122],"genre_scores_gemma":[0.9791246,0.004445887,0.01308745,0.00005687657,0.00001797372,0.00006613194,0.0005321115,0.00006012131,0.00260878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001207837,"threshold_uncertainty_score":0.003054857,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06347840210144128,"score_gpt":0.34284705412343,"score_spread":0.2793686520219887,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}