{"id":"W2033489887","doi":"10.2174/1570161112666140226123139","title":"Ca&lt;sup&gt;2+&lt;/sup&gt;/Calmodulin-Dependent Protein Kinase- II in Vasoactive Peptide- Induced Responses and Vascular Biology","year":2014,"lang":"en","type":"review","venue":"Current Vascular Pharmacology","topic":"Signaling Pathways in Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Espace pour la vie","funders":"Canadian Institutes of Health Research","keywords":"Vasoactive; Calmodulin; Vasoactive intestinal peptide; Protein kinase A; Peptide; Cell biology; Endocrinology; Molecular biology; Kinase; Internal medicine; Chemistry; Biology; Medicine; Biochemistry; Calcium; Neuropeptide; Receptor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.002273679,0.00169224,0.003129391,0.000711536,0.0003676864,0.00006230085,0.001411487,0.001820742,0.0002574289],"category_scores_gemma":[0.0006611135,0.001633544,0.001577351,0.0005376648,0.0006081607,0.00002076391,0.001715531,0.001599324,0.000127806],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003404835,"about_ca_system_score_gemma":0.001286785,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002433471,"about_ca_topic_score_gemma":0.00001775558,"domain_scores_codex":[0.9887146,0.004640512,0.001669789,0.002924225,0.0005330266,0.001517873],"domain_scores_gemma":[0.9963593,0.0002608008,0.0008423311,0.001542664,0.0003223598,0.0006725101],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008930661,0.004174504,0.0003048972,0.02393893,0.01091178,0.0002709447,0.0004477356,0.0002339445,0.3367366,0.0004468715,0.006115926,0.6155248],"study_design_scores_gemma":[0.003659789,0.0008518226,0.00004368077,0.002017057,0.003085572,0.00005865731,0.00001402024,0.0001089914,0.007035745,0.0000946223,0.981222,0.001808084],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1891938,0.8049989,0.0002444722,0.00003597482,0.001315666,0.003705193,0.0003709051,0.00007456481,0.00006050511],"genre_scores_gemma":[0.03619371,0.9561892,0.0002003388,0.0001580345,0.001828387,0.003041081,0.00193504,0.0003088885,0.0001453783],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9751061,"threshold_uncertainty_score":0.9995824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04135828214120942,"score_gpt":0.3554352340151425,"score_spread":0.3140769518739331,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}