{"id":"W2033523953","doi":"10.1210/en.2002-220251","title":"Cellular Specificity of Proexendin-4 Processing in Mammalian Cells<i>in Vitro</i>and<i>in Vivo</i>","year":2002,"lang":"en","type":"article","venue":"Endocrinology","topic":"Neuropeptides and Animal Physiology","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto","funders":"","keywords":"Prohormone convertase; Ex vivo; Prohormone; Furin; Biology; Internal medicine; Endocrinology; Proglucagon; Transfection; Enteroendocrine cell; Molecular biology; Cell culture; In vitro; Biochemistry; Glucagon-like peptide-1; Hormone; Endocrine system; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000317336,0.0002839145,0.0002241365,0.0001890073,0.0002259849,0.0007610063,0.0002711836,0.000261434,0.001612294],"category_scores_gemma":[0.0001976287,0.0001902358,0.0003434363,0.0001399875,0.0002696452,0.0002945112,0.0002494558,0.0005533174,0.001104972],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004284992,"about_ca_system_score_gemma":0.0001966857,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007678281,"about_ca_topic_score_gemma":0.0008891565,"domain_scores_codex":[0.999605,0.00008455927,0.00005462786,0.0001079407,0.0000846695,0.00006327908],"domain_scores_gemma":[0.999763,0.00008192028,0.00005101708,0.00004467379,0.00002893487,0.00003049436],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007474143,0.00001192633,0.000138922,0.00003143779,0.000004579537,0.00002921027,0.00001815626,0.00001833801,0.9992321,0.00007692719,0.00002705464,0.0003367335],"study_design_scores_gemma":[0.00001177199,0.000133464,0.007128184,0.000009931205,0.00002013457,0.0002831382,0.00004712223,0.0005461249,0.9883866,0.00003614503,0.003391149,0.000006247818],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9720416,0.006328112,0.01313971,0.0002603901,0.0001078738,0.00007819598,0.001541871,0.0001429164,0.006359459],"genre_scores_gemma":[0.9704472,0.004301033,0.01222677,0.0002301079,0.00005638822,0.0001492567,0.005580305,0.00006635443,0.006942593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001612294,"threshold_uncertainty_score":0.005393684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03191675471464941,"score_gpt":0.2377076698517901,"score_spread":0.2057909151371407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}