{"id":"W2033561289","doi":"10.1159/000232999","title":"Suppression of IgE Antibody Production in Sensitized Mice and Rats by Tolerogenic Conjugates of Synthetic Hydrophilic Polymers with Antigen or Hapten: Effect on Antigen-Induced Histamine Release from Peritoneal Mast Cells","year":2009,"lang":"en","type":"article","venue":"International Archives of Allergy and Applied Immunology","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Immunoglobulin E; Histamine; Antigen; Immunology; Ovalbumin; Antibody; Radioallergosorbent test; Hapten; Medicine; Chemistry; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003966385,0.001282234,0.0004540899,0.0006638264,0.0001897496,0.0002896581,0.0003805863,0.0006630076,0.001417039],"category_scores_gemma":[0.0002447095,0.0003863167,0.0006071786,0.0001796982,0.0005404627,0.0004098415,0.0002792653,0.001288871,0.0003635412],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002850724,"about_ca_system_score_gemma":0.0002431971,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000348132,"about_ca_topic_score_gemma":0.0004399211,"domain_scores_codex":[0.9996474,0.00005922996,0.00002459441,0.00006610756,0.00007363404,0.0001290831],"domain_scores_gemma":[0.9996499,0.00004507373,0.0001083492,0.00005188974,0.00002183528,0.0001230358],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006303742,0.0002163611,0.0001766691,0.00002464138,0.000005560256,0.00004619853,0.00001747327,0.00005346208,0.997956,0.00006433512,0.00001408846,0.0007948279],"study_design_scores_gemma":[0.000176369,0.007373086,0.004333606,0.000006577572,0.00004465184,0.0002132247,0.00002242471,0.0004488996,0.9867542,0.00006435478,0.0005540958,0.000008451258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981482,0.0004020914,0.0008896383,0.00004617809,0.00002207752,0.00002926933,0.00008633376,0.00006509049,0.0003112077],"genre_scores_gemma":[0.9957473,0.0007143553,0.001396808,0.0000762141,0.0000376458,0.000106891,0.00026136,0.00002658902,0.001632857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001417039,"threshold_uncertainty_score":0.004740477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003697322577843874,"score_gpt":0.202733788406239,"score_spread":0.1990364658283952,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}