{"id":"W2033614281","doi":"10.1002/immu.200310020","title":"Costimulation of human CD28<sup>–</sup> T cells by 4‐1BB ligand","year":2003,"lang":"en","type":"article","venue":"European Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":72,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"CD28; Biology; Cell biology; Perforin; Jurkat cells; Cytolysis; T cell; Effector; Cytokine; Immunology; Cytotoxic T cell; Immune system; CD8; In vitro; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0008491566,0.0001846728,0.0003898766,0.0002495927,0.0001566972,0.00001341019,0.0002546811,0.0001199091,0.001614766],"category_scores_gemma":[0.0001718936,0.0001646632,0.0001857389,0.0001253953,0.000217086,0.0001831776,0.00003692508,0.0006111721,0.0006045669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004737033,"about_ca_system_score_gemma":0.00003898532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006430486,"about_ca_topic_score_gemma":2.083664e-7,"domain_scores_codex":[0.9971799,0.001418056,0.0009432029,0.0001554362,0.00004809336,0.0002553641],"domain_scores_gemma":[0.9984738,0.0001245507,0.000840491,0.000243737,0.0002958766,0.00002158042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002742053,0.0001989662,0.0002545273,0.000006432792,0.0003045544,0.00001273693,0.0005161594,0.0001287886,0.9504299,0.0002680272,0.04602766,0.001578022],"study_design_scores_gemma":[0.00258892,0.001619318,0.001083061,0.00005033194,0.00006030507,0.0004696274,0.0005421112,0.000003341731,0.6850878,0.00002382329,0.308332,0.0001393523],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9701127,0.005293949,0.00102064,0.00009243986,0.002936713,0.00009971402,0.0000036372,0.00002200014,0.0204182],"genre_scores_gemma":[0.9885302,0.0002406111,0.00006122077,0.000127038,0.00003678683,4.452997e-7,0.00002882753,0.00003036675,0.0109445],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2653421,"threshold_uncertainty_score":0.9992979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01077809132483342,"score_gpt":0.2209761426367346,"score_spread":0.2101980513119012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}