{"id":"W2033671240","doi":"10.1371/journal.pone.0000312","title":"LPS Responsiveness and Neutrophil Chemotaxis In Vivo Require PMN MMP-8 Activity","year":2007,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":206,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Cancer Institute; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Centre for Blood Research, University of British Columbia; Michael Smith Health Research BC","keywords":"Chemotaxis; Chemokine; Matrix metalloproteinase; CXC chemokine receptors; Cell biology; In vivo; CXCL2; CXCL5; Chemistry; Immunology; Inflammation; Biology; Receptor; Chemokine receptor; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000220716,0.0005551417,0.0002993357,0.0003012088,0.0001254409,0.0003592171,0.0001867521,0.0004227462,0.002184028],"category_scores_gemma":[0.0001861636,0.0001852084,0.0003560182,0.00009649102,0.0003268241,0.0003212454,0.000332558,0.001055651,0.0008985359],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002991637,"about_ca_system_score_gemma":0.0001853938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001963073,"about_ca_topic_score_gemma":0.0002964168,"domain_scores_codex":[0.9996576,0.00005676658,0.00003721462,0.00005980213,0.00008412389,0.0001045268],"domain_scores_gemma":[0.9997388,0.00003797106,0.00009952769,0.00003062456,0.00002180919,0.00007131834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002311074,0.000036684,0.0002649058,0.00002487405,0.000001761957,0.00005651099,0.000008840767,0.0000239805,0.9986116,0.00005092903,0.00001568534,0.0006732186],"study_design_scores_gemma":[0.00003105916,0.0006995862,0.006704717,0.000009017859,0.000009222656,0.0004606959,0.00002221515,0.0004507928,0.990586,0.00007704675,0.0009455581,0.000004168482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920632,0.001925371,0.00375715,0.0002000324,0.00002611479,0.00006611388,0.0006690722,0.0001195527,0.001173332],"genre_scores_gemma":[0.990321,0.0008223153,0.004824673,0.00007716422,0.00002320725,0.0001420028,0.00107646,0.00002783244,0.002685306],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002184028,"threshold_uncertainty_score":0.007306337,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02275430034901208,"score_gpt":0.2331718577637202,"score_spread":0.2104175574147081,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}