{"id":"W2033726122","doi":"10.1002/dvdy.21072","title":"A switch in numb isoforms is a critical step in cortical development","year":2007,"lang":"en","type":"article","venue":"Developmental Dynamics","topic":"Nuclear Receptors and Signaling","field":"Neuroscience","cited_by":55,"is_retracted":false,"has_abstract":true,"ca_institutions":"Robarts Clinical Trials","funders":"National Center for Research Resources","keywords":"NUMB; Notch signaling pathway; Biology; Neural stem cell; Progenitor cell; Cell biology; Gene isoform; Neurogenesis; Cellular differentiation; Signal transduction; Stem cell; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001281318,0.0002943082,0.0002649285,0.0003248729,0.0003793981,0.0005145447,0.0002214797,0.0002525746,0.001860853],"category_scores_gemma":[0.0002566949,0.0003436255,0.0001717758,0.0001619539,0.0003425936,0.0004166929,0.0004342472,0.0004960026,0.0006162006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004446628,"about_ca_system_score_gemma":0.0003360344,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007048633,"about_ca_topic_score_gemma":0.001517267,"domain_scores_codex":[0.9998645,0.0000117614,0.00001161773,0.00004131889,0.00004082957,0.00002999353],"domain_scores_gemma":[0.9998505,0.00001595633,0.00004931205,0.00001826034,0.00001570691,0.00005016993],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005821681,0.000005970276,0.0005560485,0.00001583881,0.000002534489,0.00009650795,0.00001531593,0.000044652,0.9968024,0.0002179298,0.00002344179,0.002161064],"study_design_scores_gemma":[0.00001087157,0.00008758892,0.02996459,0.00001357038,0.000008842979,0.0007908816,0.00008804812,0.0006225558,0.9625719,0.0003681721,0.005464869,0.000008185043],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912698,0.001886519,0.00400789,0.00008953334,0.00002398415,0.00002046822,0.0002210376,0.0001269828,0.002353841],"genre_scores_gemma":[0.9895374,0.001466721,0.00356239,0.00004208891,0.000008311345,0.00004247966,0.0002907502,0.00004527529,0.005004645],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001860853,"threshold_uncertainty_score":0.006225169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02173921785843558,"score_gpt":0.2833165283526087,"score_spread":0.2615773104941732,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}