{"id":"W2033744598","doi":"10.1016/j.ijrobp.2004.01.002","title":"Phase I study pilot arms of radiotherapy and carmustine with temozolomide for anaplastic astrocytoma (Radiation Therapy Oncology Group 9813): implications for studies testing initial treatment of brain tumors","year":2004,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; University of Calgary","funders":"National Cancer Institute; Central China Normal University","keywords":"Carmustine; Medicine; Anaplastic astrocytoma; Temozolomide; Lomustine; Radiation therapy; Astrocytoma; Glioma; Oncology; Nitrosourea; Internal medicine; Chemotherapy; Etoposide; Cyclophosphamide; Cancer research; Vincristine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00351919,0.002813319,0.004210517,0.001037874,0.001220396,0.001681392,0.002463026,0.003191388,0.008114356],"category_scores_gemma":[0.002932137,0.001541803,0.003669521,0.0009952541,0.002752072,0.002062195,0.0006360136,0.006960673,0.002000707],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002140896,"about_ca_system_score_gemma":0.004608122,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003412424,"about_ca_topic_score_gemma":0.006961633,"domain_scores_codex":[0.9985036,0.0007237536,0.00006837938,0.0002387727,0.000102234,0.0003633159],"domain_scores_gemma":[0.9958766,0.00085609,0.0006773063,0.0005016151,0.0003091388,0.001779322],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9143117,0.05999526,0.001046593,0.0001637084,0.0007563579,0.00006995576,0.0001352309,0.0007776244,0.008363256,0.0001605585,0.001678312,0.01254148],"study_design_scores_gemma":[0.5952568,0.3985833,0.002490584,0.00001122745,0.0004405204,0.00006813765,0.00005137103,0.0003179773,0.001740938,0.0002119672,0.0008062511,0.00002086457],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841338,0.001000346,0.0009097318,0.0009790215,0.000377546,0.00706436,0.003138738,0.0001586856,0.002237719],"genre_scores_gemma":[0.9631571,0.001355508,0.005259892,0.001405904,0.0005574508,0.01795061,0.004831522,0.0001107082,0.005371397],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008114356,"threshold_uncertainty_score":0.02714527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07662883297039721,"score_gpt":0.4196632941954061,"score_spread":0.3430344612250089,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}