{"id":"W2033782334","doi":"10.1186/1471-2407-10-655","title":"14-3-3 zeta is a molecular target in guggulsterone induced apoptosis in Head and Neck cancer cells","year":2010,"lang":"en","type":"article","venue":"BMC Cancer","topic":"Pharmacological Effects of Medicinal Plants","field":"Medicine","cited_by":48,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mount Sinai Hospital; University of Toronto; York University","funders":"Mitacs; Council of Scientific and Industrial Research, India; University of Toronto; Ontario Institute for Cancer Research","keywords":"Apoptosis; Cancer research; Head and neck squamous-cell carcinoma; Cancer cell; Cancer; Biology; Medicine; Molecular biology; Head and neck cancer; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002754053,0.0002250708,0.0005075723,0.0001795763,0.00001930491,0.00001356766,0.0001237566,0.0002257363,0.001457869],"category_scores_gemma":[0.0001045449,0.0001854881,0.00004615618,0.0002993943,0.00007697969,0.00009281094,0.00007633187,0.0007706689,0.00002167713],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001392412,"about_ca_system_score_gemma":0.0002196962,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005367563,"about_ca_topic_score_gemma":0.004334332,"domain_scores_codex":[0.9984329,0.0000601473,0.00029616,0.0004381875,0.0003238329,0.0004487184],"domain_scores_gemma":[0.9992924,0.000103661,0.00007673861,0.0002114247,0.00004388301,0.0002719217],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005566778,0.0001613885,0.09439781,0.000207268,0.00002447949,0.00009691568,0.0002390026,0.00002281181,0.8972787,0.000003008262,0.003152327,0.003859599],"study_design_scores_gemma":[0.009053339,0.0003505685,0.3154872,0.0007148125,0.00008776425,0.00001635316,0.00003659603,0.0009982846,0.6695284,0.00006831847,0.003323426,0.0003348987],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994038,0.001340018,0.000006731872,0.002284484,0.0006758076,0.0007527193,0.00003707852,0.00002717947,0.0008379773],"genre_scores_gemma":[0.991874,0.0002953683,0.0006177137,0.006574672,0.0001972186,0.0002118542,0.000005758291,0.00002588553,0.0001975163],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2277503,"threshold_uncertainty_score":0.9994549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02860696799311595,"score_gpt":0.3477402569111917,"score_spread":0.3191332889180757,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}